SzSA YearBook 2016/17

SZENT-GYÖRGYI JUNIOR MENTORS
MÁTÉ MANCZINGER
University of Szeged,
Department of Dermatology and Allergology
Address: Korányi fasor 6., H-6720 Szeged, Hungary
E: manczinger.mate@med.u-szeged.hu
T: +36 62/545-260
RESEARCH AREA
The adaptive immune system has to differentiate between
harmful and non-harmful agents. If differentiation is insufficient,
either defense against pathogens is inappropriate or
recognition of non-harmful peptides leads to allergy and
autoimmunity. All of these indicate, that immune recognition
is complex, but finely tuned at the same time. In our
research, we examine adaptive immune recognition and its
role in the pathogenesis of diseases. We are investigating
infectious, autoimmune diseases and asthma at present.
Additionally, the role of adaptive immunity in antitumor defense
is also being examined. We mainly use bioinformatic
tools for our analyses.
TECHNIQUES AVAILABLE IN THE LAB
Programming in “R” language. Big data analysis, Statistical
analysis, database processing, immunoinformatic analysis.
SELECTED PUBLICATIONS
Manczinger, M., Kemény, L. (2016) Method and nontransitory
computer-readable computer program product
for identification of effective drugs. US Patent App 15:
198,366.
Manczinger, M., Bocsik, A., Kocsis, G.F., Vörös, A., Hegedűs,
Z., Ördögh, L., Kondorosi, É., Marton, A., Vízler, C., Tubak, V.,
Deli, M., Kemény, L., Nagy, I., Lakatos, L. (2015) The absence
of N-Acetyl-D-glucosamine causes attenuation of virulence
of Candida albicans upon interaction with vaginal epithelial
cells in vitro. Biomed Res Int 2015: 398045.
Manczinger, M., Kemény, L. (2013) Novel factors in the
pathogenesis of psoriasis and potential drug candidates are
found with systems biology approach. PLOS ONE 8: e80751.
Manczinger, M., Szabó, E.Z., Göblös, A., Kemény, L., Lakatos,
L. (2012) Switching on RNA silencing suppressor activity by
restoring argonaute binding to a viral protein. J Virol 86:
8324-7.
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