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SzSA YearBook 2016/17

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SZENT-GYÖRGYI MENTORS<br />

SZABOLCS KÉRI<br />

Department of Physiology,<br />

University of Szeged<br />

Address: Dóm tér 10., H-6720 Szeged, Hungary<br />

E: keri.szabolcs.gyula@med.u-szeged.hu<br />

T: +36 62/545 101<br />

RESEARCH AREA<br />

Understanding the basic mechanisms of psychiatric disorders<br />

(schizophrenia, depression, posttraumatic reactions)<br />

is an ultimate challenge for sciences, humanities, and<br />

arts. Our team is dedicated to the delineation of the meeting-point<br />

of these traditionally remote areas of exploration<br />

and discovery, using the tools of neurosciences and psychology.<br />

Beyond the clinical symptoms, we pay an outstanding attention<br />

to the basic cognitive building blocks of psychiatric<br />

disorders (e.g., dysfunctions of perception, attention, and<br />

memory), their neurobiological background, and finally we<br />

seek the link between these fundamental functions and<br />

higher human phenomena (e.g., the impact of psychological<br />

trauma, the relationship among psychotherapy, healing,<br />

and creativity).<br />

What is the relationship between the pathophysiology of<br />

perception and memory and the symptom clusters of hallucinations<br />

and delusions? Why are these symptoms more<br />

common in immigrants and refugees? What is the role of<br />

psychological trauma? What kind of structural and functional<br />

brain plasticity can be found behind the response to<br />

psychotherapy? Is there any chance to find a relationship<br />

between these changes and the molecular mechanisms?<br />

Where is the boundary between medical sciences and humanities?<br />

The research team works at three centers in a strong collaborative<br />

network with several psychiatric units: in addition<br />

to the Department of Physiology at the medical faculty of<br />

the University of Szeged, the network includes the National<br />

Institute for Psychiatry and Addictions, and the Department<br />

of Cognitive Science of Budapest University of Technology<br />

and Economics.<br />

TECHNIQUES AVAILABLE IN THE LAB<br />

Clinical interview and rating scales, narrative deep interview,<br />

administration and development of neuropsychological tests<br />

(SuperCard and E-Prime programming environments), eyetracking,<br />

EEG, structural brain measurements with magnetic<br />

resonance imaging (MRI), development and clinical validation<br />

of biochip technologies.<br />

SELECTED PUBLICATIONS<br />

Szily, E., Kéri, Sz. (2013) Delusion proneness and emotion<br />

appraisal in individuals with high psychosis vulnerability.<br />

Clin Psychol Psychother 20: 166-70.<br />

Levy-Gigi, E., Kéri, Sz. (2012) Falling out of time: enhanced<br />

memory for scenes presented at behaviorally irrelevant<br />

points in time in posttraumatic stress disorder (PTSD). PLoS<br />

One 7: e42502.<br />

Kéri, Sz. (2011) Solitary minds and social capital: Latent<br />

inhibition, general intellectual functions and social network<br />

size predict creative achievements. Psychol Aesthet Creat<br />

Arts 5: 215-221.<br />

Kéri, Sz., Moustafa, A.A., Myers, C.E., Benedek, G., Gluck, M.A.<br />

(2010) Alpha-Synuclein gene duplication impairs reward<br />

learning. Proc Natl Acad Sci USA 107: 15992-4.<br />

Kéri, Sz., Beniczky, S., Kelemen, O. (2010) Suppression of the<br />

P50 evoked response and neuregulin 1-induced AKT phosphorylation<br />

in first-episode schizophrenia. Am J Psychiatry<br />

167: 444-50.<br />

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