SzSA YearBook 2016/17
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SZENT-GYÖRGYI STUDENTS<br />
PETRA VARGA<br />
Szeged Scientists Academy, 1 st year<br />
University of Szeged,<br />
Faculty of Medicine, 1 st year<br />
E: vpetra9998@gmail.com<br />
T: +36 20/379-9819<br />
DATE OF BIRTH:<br />
1998<br />
SZENT-GYÖRGYI PUPIL:<br />
yes<br />
SZENT-GYÖRGYI MENTOR:<br />
Dr. Mihály Boros<br />
SPECIALTY:<br />
circulation physiology and<br />
pathophysiology<br />
SECONDARY SCHOOL:<br />
Radnóti Miklós Experimental<br />
Grammar School, Szeged<br />
NAME OF TEACHER:<br />
Sándor Bán<br />
LANGUAGES:<br />
English/advanced<br />
German/intermediate<br />
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />
Tissue ischemia developing upon vascular occlusion and subsequent reperfusion<br />
often leads to severe organ damage and inflammation, but there is no effective<br />
prevention and treatment available to date. Our goal is to precisely characterize<br />
the above processes in order to develop new therapeutic strategies. Biologically<br />
active gases modulate crucial steps in such disorders, with nitric oxide and its<br />
metabolites playing a principal role. Generation and beneficial effects of methane<br />
were repeatedly proven in various animal models of ischemia-reperfusion<br />
and inflammation in our laboratory, thus demonstrating biological activity of<br />
the molecule. However, the mechanism of action of methane still needs to be<br />
clarified. Our research focuses on the interplay of methane and nitric oxide in various<br />
models of oxidative stress. Methane might exert its effects by modulating<br />
generation of peroxynitrite, which is an extremely reactive oxygen and nitrogen<br />
containing molecule or alternatively, methane may influence protein nitration<br />
by peroxynitrite. We use photoacoustic spectroscopy to assess generation of gaseous<br />
compounds and among others fluorescence and chemiluminescence to<br />
measure generation of reactive oxygen and nitrogen species.<br />
AIMS DURING HER CAREER<br />
After graduation I would like to work in a hospital as a doctor. In addition, I plan<br />
to take part in the development of medicine with research work. I think it is important<br />
to spread the modern tools and methods of medicine.<br />
HONORS AND PRIZES<br />
• International Biology Olympiad: silver medal<br />
• European Union Science Olympiad: gold medal<br />
• International Genetically Engineered Machine: Best Experimental Measurement<br />
• National Biology Competition: 4 th place, 15 th place<br />
• Dr. Árokszállásy Zoltán Biology Competition: 3 rd place, 9 th place<br />
• Arany Dániel Mathematics Competition: 3 rd place<br />
• Szécsi Szilveszter Prize (for the best female student in the grammar school)<br />
PUBLICATIONS<br />
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128
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