SzSA YearBook 2016/17
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RÉKA TÓTH<br />
SZENT-GYÖRGYI STUDENTS<br />
Szeged Scientists Academy, 3 rd year<br />
University of Szeged,<br />
Faculty of Medicine, 3 rd year<br />
E: tothrek@outlook.com<br />
T: +36 30/547-3457<br />
DATE OF BIRTH:<br />
1995<br />
SZENT-GYÖRGYI PUPIL:<br />
yes<br />
SZENT-GYÖRGYI MENTOR:<br />
Dr. Eszter Farkas<br />
SPECIALTY:<br />
neurology<br />
SECONDARY SCHOOL:<br />
SZTE Ságvári Endre Secondary<br />
School, Szeged<br />
NAME OF TEACHER:<br />
István Csigér<br />
LANGUAGES:<br />
English/advanced<br />
French/intermediate<br />
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />
Stroke is the third most common cause of death in Hungary and Europe coming<br />
only after heart disease and cancer. Recurrent spreading depolarizations (SDs)<br />
spontaneously occur in the cerebral cortex after experimental induction of focal<br />
ischemia. SDs generate consistently and repeatedly in the injured human brain<br />
for at least over a week after the initial trauma, and contribute to lesion progression<br />
by worsening the perfusion of penumbra tissue. The central goal of our<br />
research is to understand the mechanisms that mediate the SD-coupled cerebral<br />
blood flow response and SD related neurodegeneration. Ultimately, we aim to<br />
identify targets to counteract the evolution of injurious spreading depolarizations<br />
and limit the progression of secondary injury. Our methodological approach<br />
includes classic electrophysiology, the use of ion selective microelectrodes,<br />
cerebral blood flow monitoring, and novel, experimental, optical neuroimaging.<br />
AIMS DURING HER CAREER<br />
I would like to use the experience and knowledge that I acquire during my work,<br />
regardless of whether I will be working in fundamental research or clinical research,<br />
After finishing the university I would also like to start working on my PhD<br />
degree.<br />
HONORS AND PRIZES<br />
–<br />
PUBLICATIONS<br />
Varga, D.P., Puskás, T., Menyhárt, Á., Hertelendy, P., Zölei-Szénási, D., Tóth, R.,<br />
Ivánkovits-Kiss, O., Bari, F., Farkas, E. (<strong>2016</strong>) Contribution of prostanoid signaling<br />
to the evolution of spreading depolarization and the associated cerebral blood<br />
flow response. Sci Rep 10: 31402.<br />
Puskás, T., Tóth, R., Menyhárt, Á., Ivánkovits-Kiss, O., Bari, F., Farkas, E. In vitro examination<br />
of spreading depolarizations: establishing a new experimental setup<br />
and protocol. Poszter, IBRO <strong>2016</strong>.<br />
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