08.09.2017 Views

SzSA YearBook 2016/17

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

SZENT-GYÖRGYI STUDENTS<br />

BERNÁT NÓGRÁDI<br />

Szeged Scientists Academy, 2 nd year<br />

University of Szeged,<br />

Faculty of Medicine, 2 nd year<br />

E: bernatnogradi@gmail.com<br />

T: +36 20/590-6907<br />

DATE OF BIRTH:<br />

1997<br />

SZENT-GYÖRGYI PUPIL:<br />

no<br />

SZENT-GYÖRGYI MENTOR:<br />

Dr. László Siklós<br />

JUNIOR MENTOR:<br />

Dr. Roland Patai<br />

SPECIALTY:<br />

neuroscience<br />

SECONDARY SCHOOL:<br />

Deák Ferenc Secondary<br />

School, Szeged<br />

NAME OF TEACHER:<br />

Jennifer Tusz<br />

LANGUAGES:<br />

German/intermediate<br />

English/advanced<br />

Chinese/basic<br />

IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />

Our research group studies the etiology and the complex pathomechanisms of<br />

neuronal degeneration and other malicious events which can lead to neuronal<br />

death. Amongst degenerative diseases that take place in the central nervous<br />

system we focus on amyotrophic lateral sclerosis, one of the most common pathological<br />

conditions that can be characterized by the progressive loss of motor<br />

neurons. Our aim is to reveal and understand the complex pathological mechanisms<br />

from the level of the nervous circuits to the level of a single motor neuron,<br />

moreover, find possible therapeutic approaches. Last but not least our micro-anatomical<br />

research is aimed to derive quantitative data characterizing nerve cells in<br />

healthy conditions, during disease and ageing, which are also suitable to measure<br />

the effect of treatments aimed to halt or reverse disease progression.<br />

AIMS DURING HIS CAREER<br />

My aim is to elucidate the pathomechanisms of acute and chronic neuronal degeneration<br />

that can open new therapeutic approaches in the long run. As for<br />

my scientific approach, I share my mentors’ point of view that a scientist must sit<br />

down to a microscope and stand next to a patient with the same determination<br />

and enthusiasm, because in both cases the most important is to give hope to the<br />

people who suffer from the disease.<br />

HONORS AND PRIZES<br />

• 2013 – “Experiments in fluid and gas dynamics” – Competition in Applied<br />

Physics for High School Students (2 nd Prize)<br />

• 2013 – Katalin Varga Scientific Symposium (3 rd Prize)<br />

PUBLICATIONS<br />

Patai, R., Nógrádi, B., Obál, I., Engelhardt, J.I., Siklós, L. (<strong>2016</strong>) Calcium in the pathomechanism<br />

of amyotrophic lateral sclerosis – taking center stage? Biochem Biophys<br />

Res Commun 483: 1031-1039.<br />

Meszlényi, V., Patai, R., Nógrádi, B., Engelhardt, J.I., Siklós, L. (20<strong>17</strong>) Commentary:<br />

Calcium in the pathomechanism of amyotrophic lateral sclerosis - Taking center<br />

stage? J Neurol Neuromed (under revision)<br />

Patai, R., Nógrádi, B., Meszlényi, V., Obál, I., Engelhardt, J.I., Siklós, L. (20<strong>17</strong>) Az amiotrófiás<br />

laterálszklerózis patofiziológiai tényezőinek központi kapcsolóeleme, a<br />

kalcium. Ideggy Szle (in press)<br />

113

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!