SzSA YearBook 2016/17

SZENT-GYÖRGYI STUDENTS
VALÉRIA ÉVA MESZLÉNYI
Szeged Scientists Academy, 1 st year
University of Szeged,
Faculty of Medicine, 2 nd year
E: mesval13@gmail.com
T: +36 30/914-9107
DATE OF BIRTH:
1996
SZENT-GYÖRGYI PUPIL:
no
SZENT-GYÖRGYI MENTOR:
Dr. László Siklós
SPECIALTY:
neuroscience
SECONDARY SCHOOL:
Petőfi Sándor Secondary
School, Bonyhád
NAME OF TEACHER:
Andrea Nagy
LANGUAGES:
English/intermediate
German/intermediate
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH
Our research unit is devoted to study the operation of the nervous system in
physiological and pathological conditions. There are many neurodegenerative
diseases, however, we focus on the amyotrophic lateral sclerosis which is the
most common degenerative disease of the motor neuron system.
Our main goal is to understand the complex mechanism and consequences of
the disease furthermore to find possible therapeutic approaches. In our current
experiments we would like to investigate the changes in communication
of motor neurons and their neighboring non-neuronal cells in their natural environment
with the acute and chronic neurodegenerative animal models in vivo.
From methodological point of view we rely on geometrical statistically derived
biologically relevant three-dimensional parameters acquired by basic structural
investigations (light, fluorescent, and electron microscopic techniques), and biological
structural research, labeling techniques for molecular imaging.
AIMS DURING HER CAREER
In the course of my scientific career I would like to study and understand the
primary factors leading to the wide spectra of neurodegeneration and pathomechanisms
of neuronal death. My aim is to accumulate proper knowledge
that can serve the human society and medical science. I hope it will give me a
possibility to contribute to development of novel therapeutic approaches.
HONORS AND PRIZES
• 2015. Medallion of János Lotz (Silver Prize)
• 2015. 8 th Dürer Competition in Chemistry (2 nd Prize)
• 2014. SZTE Szent-Györgyi Educational Competition (3 rd Prize)
• 2014. 7 th Dürer Competition in Chemistry (3 rd Prize)
• 2010. Talentum Prize obtained from Tolna County
PUBLICATIONS
Patai, R., Nógrádi, B., Meszlényi, V., Obál, I., Engelhardt, J.I., Siklós, L. (2017) Calcium
ion is a common denominator in the pathophysiological processes of amyotrophic
lateral sclerosis. Clin Neurosci (in press)
Meszlényi, V., Patai, R., Nógrádi, B., Engelhardt, J.I., Siklós, L. (2017) Commentary:
Calcium in the pathomechanism of amyotrophic lateral sclerosis - Taking center
stage? J Neurol Neuromed (under review)
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