SzSA YearBook 2016/17
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SZENT-GYÖRGYI STUDENTS<br />
SÁRA NOÉMI MAGYAR<br />
Szeged Scientists Academy, 2 nd year<br />
University of Szeged,<br />
Faculty of Medicine, 2 nd year<br />
E: sara.magyar08@gmail.com<br />
T: +36 30/4456-434<br />
DATE OF BIRTH:<br />
1996<br />
SZENT-GYÖRGYI PUPIL:<br />
yes<br />
SZENT-GYÖRGYI MENTOR:<br />
Dr. László Vígh<br />
JUNIOR MENTOR:<br />
Bálint Csoboz<br />
SPECIALTY:<br />
molecular stressbiology<br />
SECONDARY SCHOOL:<br />
Berze Nagy János Secondary<br />
School, Gyöngyös<br />
NAME OF TEACHER:<br />
Katalin Molnárné Borbás<br />
LANGUAGES:<br />
English/intermediate<br />
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH<br />
Ionizing radiation combined with chemotherapy and surgery are the key current<br />
therapeutic approaches to cancer. Despite enormous progress made in the<br />
instrumentation for delivery of radiotherapy the clinical outcome still remains<br />
unsatisfactory. The damage of the surrounding non-cancerous tissues upon radiation<br />
limits the efficacy of radiation therapy. In order to be able to circumvent<br />
these limitations molecular factors and mechanisms that could alleviate tissue<br />
damage upon radiation have come to the focus of oncological research. From<br />
the wide array of such possible candidates a family of proteins termed as heat<br />
shock proteins (HSPs) has gained more and more attention in recent years in<br />
the context of cellular survival upon radiation damage. Heat shock protein are<br />
general stress proteins activated upon a great variety of stress conditions including<br />
gamma irradiation. In this study we are aiming to understand the induction<br />
kinetics of HSPs in non-cancerous and cancerous cells upon radiation therapy. In<br />
order to characterize a possible point of interference where HSP inducing treatments<br />
could be utilized to enhance radiation induced survival in non-malignant<br />
tissues without the side effect of inducing tumor survival. The data gained from<br />
this study could possibly further the limits of currently used anti-cancer radiation<br />
therapies.<br />
AIMS DURING HER CAREER<br />
I have not decided whether to become a doctor or researcher. Both of them are<br />
great choices, have lots of chances and have an effect on the medical system. I<br />
would like to experience both and afterwards I can make the perfect decision.<br />
HONORS AND PRIZES<br />
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PUBLICATIONS<br />
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107
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