SzSA YearBook 2016/17

SZENT-GYÖRGYI STUDENTS
DÉNES PÉTER KOVÁCS
Szeged Scientists Academy, 1 st year
University of Szeged,
Faculty of Medicine, 2 nd year
E: kovacsdenespeter@gmail.com
T: +36 20/539-6141
DATE OF BIRTH:
1994
SZENT-GYÖRGYI PUPIL:
no
SZENT-GYÖRGYI MENTOR:
Dr. Zoltán Rakonczay
JUNIOR MENTOR:
Dr. Lóránd Kiss
SPECIALTY:
gastroenterology
SECONDARY SCHOOL:
Árpád Secondary School,
Budapest
NAME OF TEACHER:
Róbert Kiss
LANGUAGES:
English/advanced
IMPORTANCE, AIMS AND POSSIBLE OUTCOME OF RESEARCH
Our team investigates the pathogenesis of acute pancreatitis (AP), a sudden
inflammatory disorder of the pancreas. This disorder of the gastrointestinal system
affects thousands of people in our country each year, and has a significant
mortality rate. The causes of AP include biliary disease related to gall stones, improper
alcohol or food intake, genetic defects, as well as high serum triglyceride
level.
We model the disease in rodents (mice, rats) using retrograde intraductal infusion
of bile acids, or intraperitoneal injections of the cholecystokinin analogue
cerulein or basic amino acids (L-arginine or L-ornithine). After the induction of
AP, we isolate ducts or acinar cells from the pancreas and observe them. We investigate
the mRNA expression of ion transporters with immunohistochemistry,
Polymerase Chain Reaction (PCR) and Western blot technique. By intracellular pH
measurement and patch clamp technique, we study the functions of ion channels.
Our main goals are to understand the role of these transport proteins, their
changes caused by AP, and to use this knowledge to work out novel treatments.
AIMS DURING HIS CAREER
My goal is to improve and extend my knowledge, this is the reason I applied to
this program. My long-term intentions are to become an unexceptional expert,
and to see my efforts bring success. I hope that through these achievements,
treatment of the disease will advance.
HONORS AND PRIZES
Attendance at:
• OKTV Biology 2011, 2012
• Sándor Mikola Physics competition 2009, 2010
PUBLICATIONS
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106