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y Heather Smith Thomas<br />

Equine influenza is caused by a virus<br />

and is one of the most common<br />

infectious diseases of the <strong>res</strong>piratory<br />

tract of horses. It is endemic in the<br />

equine population of the United<br />

States and throughout much of the world,<br />

where young horses aged one to five are<br />

generally the most susceptible. Older<br />

horses may have some immunity if they<br />

have previously encountered the virus.<br />

Equine Influenza is one of the diseases a<br />

horse might be exposed to when leaving<br />

the farm and going to the racetrack.<br />

Mark Crisman DVM, who is the Senior<br />

Veterinarian at Equine Technical Services,<br />

Zoetis in Blacksburg, Virginia, works for<br />

Zoetis and also teaches at the University.<br />

He says equine influenza has been around<br />

for centuries—with outbreaks recorded<br />

throughout North America and Europe.<br />

“One incident that really got our attention<br />

was the outbreak in Australia in 2007.<br />

Australia had been influenza-free, so horse<br />

owners there did not vaccinate for this<br />

disease. It came in to that continent with<br />

an imported horse and the native equine<br />

population was completely susceptible,”<br />

he says.<br />

“More than 10,000 premises (and<br />

all the horses on those premises) were<br />

affected. Australia spent more than a billion<br />

dollars getting that outbreak <strong>res</strong>olved,” says<br />

Crisman.<br />

“The incubation period for this<br />

<strong>res</strong>piratory disease is very short—just a<br />

couple of days. We’ve seen outbreaks that<br />

literally swept through a stable or barn,<br />

and in a teaching hospital, where within<br />

48 hours every horse in the barn was<br />

coughing,” he says.<br />

The clinical signs include fever, cough<br />

and nasal discharge. “I’ve seen fevers up<br />

to 104 degrees and 105 and higher with<br />

influenza. The horse also has a harsh, dry<br />

cough. During that phase, the virus is<br />

being aerosolized and can be spread quite<br />

a distance just from the coughing and<br />

sneezing.” If another horse is downwind<br />

from the horse that is coughing, it may<br />

inhale some of those virus-bearing droplets.<br />

“The viral infection usually runs its<br />

course quickly,” says Crisman. It attacks<br />

the epithelium in the upper airways and<br />

damages this lining (and the cilia), but this<br />

damage will heal within one to three weeks<br />

if there are no secondary complications.<br />

Exercising a horse too soon after infection can<br />

cause secondary issues. The deep breathing in of<br />

dust and debris draws it into the airways and can<br />

create a <strong>res</strong>piratory infection.<br />

Ty Wyant<br />

“The length/duration of viremia (virus<br />

in the blood), which is the period of time<br />

the virus is being shed and can be spread<br />

to another horse, depends on existing<br />

immunity of that particular horse. For<br />

instance, in Australia, where there were<br />

many naïve horses, the disease basically ran<br />

amok. Here in the U.S., it’s a bit different<br />

because many horses have had some<br />

exposure and have some immunity because<br />

they are generally vaccinated, which gives<br />

some protection,” he says.<br />

“The severity of clinical signs can vary<br />

a great deal. Horses with some level of<br />

immunity, such as recent vaccinations,<br />

won’t be as sick and won’t shed the virus<br />

as long. We tell horse owners that they<br />

should <strong>res</strong>t the horse one week for every<br />

day of fever.” In other words, if the horse<br />

had a fever for only one day, a week of <strong>res</strong>t<br />

might be adequate, whereas if the horse<br />

had a fever for three days, you should <strong>res</strong>t<br />

him for at least three weeks before working<br />

him again, even if he feels good before that<br />

time is up.<br />

“The virus attacks the epithelium<br />

in the upper airway. The upper airway<br />

is designed to be a major defense<br />

component of the horse’s immune<br />

system,” he says. This is the first line of<br />

defense to ensure that pathogens don’t get<br />

down into the lungs.<br />

Bacteria and other pathogens exist in<br />

the upper airway, inhaled by the horse. The<br />

tiny cilia (hair-like “fingers” that line the<br />

epithelium) constantly move in wavelike<br />

motion to move dust or any other inhaled<br />

debris—including pathogens—up out of<br />

the airway so they can be coughed out or<br />

swal<strong>low</strong>ed, keeping them out of the lungs.<br />

30 New Mexico Horse Breeder

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