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Pentose-Fermenting Zymomonas mobilis - EERE - U.S. Department ...

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Metabolic Engineering for <strong>Pentose</strong> Fermentation<br />

<strong>Pentose</strong> Metabolism Pathway<br />

D-Xylose<br />

Xylose Isomerase<br />

L-arabinose isomerase<br />

L-Ribulose<br />

L-ribulokinase<br />

D-Xylulose<br />

Xylulokinase<br />

ATP<br />

ADP<br />

L-Ribulose-5-P<br />

ATP<br />

ADP<br />

L-ribulose-5-P 4-epimerase<br />

D-Xylulose-5-P Ribulose-5-P Ribose-5-P<br />

Sedoheptulose-7-P Glyceraldehyde-3-P<br />

Erythrose-4-P<br />

Transketolase<br />

Transaldolase<br />

Transketolase<br />

L-Arabinose<br />

Fructose-6-P<br />

Fructose-6-P<br />

Glyceraldehyde-3-P<br />

Entner-Doudoroff Pathway<br />

D-Glucose<br />

Glucose-6-P<br />

Gluconolactone-6-P<br />

6-P-Gluconate<br />

2-Keto-3-deoxy-6-P-Gluconate<br />

Glyceraldehyde-3-P<br />

1,3-P-Glycerate<br />

ADP<br />

ATP<br />

3-P-Glycerate<br />

ATP<br />

ADP<br />

2-P-Glycerate<br />

ADP ATP<br />

Phosphoenolpyruvate Pyruvate<br />

Acetaldehyde + CO 2<br />

Ethanol

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