Staff Members of the Institute of Biochemistry, TU - Institut für ...

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R. Yates, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Calgary, Calgary, Canada, N. Faergeman, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark Research Projects: BM.W_F Genomforschung in Österreich (GEN-AU): Exploring the lipolytic proteome. Phospholipases (GOLD 3 project-Genomics of Lipid-associated Disorders, coordinated by KFU Graz). FWF Special Research Program (SFB) LIPOTOX (coordinated by KFU Graz): Toxicity of oxidized phospholipids in macrophages. FWF Doctoral Program Molecular Enzymology: Functional enzyme analysis. FWF EUROCORES-EuroMEMBRANE-OXPHOS-Protein targets and apoptotic signaling of oxidized phospholipids TIG Research center Applied Biocatalysis (coordinated by TU Graz): Novel lipases with specific substrate acceptance. Invited lectures: 1. Signaling of oxidized phospholipids in vascular cells. Fluorescent inhibitors for functional proteomic analysis of lipases. Biocrates, Innsbruck, January 21, 2009. 2. Toxicity of oxidized phospholipids in macrophages. COST meeting “Free radicals in Chemical Biology”, Gniezno, Poland, September 11, 2009. 3. The lipolytic proteomes of mouse adipose tissue and liver. Cornell University, Ithaca, NY, USA, September 22, 2009 4. Fluorescent inhibitors for functional proteomic analysis of lipolytic enzymes. Euro Fed Lipid, Graz, Austria, October 20, 2009 Publications: 1. Rhode S, Grurl R, Brameshuber M, Hermetter A, Schütz GJ Plasma membrane fluidity affects transient immobilization of oxidized phospholipids in endocytotic sites for subsequent uptake. J. Biol. Chem. 284, 2258-65, 2009 2. Watschinger K, Keller MA, Hermetter A, Golderer G, Werner-Felmayer G, Werner ER Glyceryl ether monooxygenase resembles aromatic amino acid hydroxylases in metal ion and tetrahydrobiopterin dependence. Biol. Chem. 390, 3-10, 2009 3. Yates RM, Hermetter A, Russell DG Recording phagosome maturation through the real-time spectrofluorometric 32
measurement of hydrolytic activities. Methods Mol. Biol. 531, 157 -171, 2009 4. Schicher M, Kollroser M, Hermetter A Mapping the lipolytic proteome of adipose tissue using fluorescent suicide inhibitors Methods Mol. Biol. 579, 497-511, 2009. 5. Morak M, Schmidinger H, Krempl P, Rechberger G, Kollroser M, Birner-Gruenberger R, Hermetter A Differential activity-based gel electrophoresis for comparative analysis of lipolytic and esterolytic activities. J. Lipid Res. 50, 1281-92, 2009. 6. Landre JB, Blaess MF, Kohl M, Schlicksbier T, Ruryk A, Kinscherf R, Claus RA, Hermetter A, Keller M, Bauer M, Deigner HP Addressable bipartite molecular hook (ABMH): Immobilized hairpin probes with sensitivity below 50 femtomolar Anal. Biochem. 2009, Epub ahead of print. 33
Page 1 and 2: Staff Members of the Institute of B
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Page 5 and 6: 2009 in Graz under the chairmanship
Page 7 and 8: The BBE-catalysed oxidative carbon-
Page 9 and 10: Nikkomycin biosynthesis Nikkomycins
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