Staff Members of the Institute of Biochemistry, TU - Institut für ...
Staff Members of the Institute of Biochemistry, TU - Institut für ... Staff Members of the Institute of Biochemistry, TU - Institut für ...
environment. In summary, this work describes biochemical and cell biological functions of neutral lipid synthesizing acyltransferases and the link to neutral lipid storage in LP. International Cooperations J. Cregg, Keck Graduate Institute of Applied Life Sciences, Claremont, CA, USA I. Hapala, Slovak Academy of Sciences, Institute of Animal Biochemistry and Genetics, Ivanka pri Dunaji, Slovak Republic I. Feussner, Plant Biochemistry, Albrecht-von-Haller-Institute of Plant Sciences, Georg- August University Göttingen, Germany R. Erdmann, Institute of Physiological Chemistry, Ruhr-University Bochum, Germany T. Höfken, Institute of Biochemistry, Christian Albrecht University, Kiel, Germany M. Karas, Institute of Pharmaceutical Chemistry, Johann Wolfgang Goethe University, Frankfurt, Germany R. Rajasekharan, Department of Biochemistry, Indian Institute of Science, Bangalore, India A. S. Sandelius, Department of Plant and Environmental Sciences, University of Gothenburg, Sweden T. Höfken, Institute of Biochemistry, Christian Albrecht University, Kiel, Germany Research Projects FWF 17321: Phosphatidylethanolamine of yeast mitochondria FWF 21429: Phosphatidylserine decarboxylase FWF 18857: Neutral lipid storage and mobilization in the yeast Saccharomyces cerevisiae FWF L-178 (Translational Research): Characterization of organelles from the yeast Pichia pastoris FWF PhD Program: Molecular Enzymology Invited Lectures 1. G. Daum University of Bochum, Germany Turnover of neutral lipids and channeling of lipid storage components in the yeast April 2009 2. G. Daum, T. Czabany, A. Wagner, K.H. Grillitsch, M. Connerth and S. Rajakumari Turnover of neutral lipids and channeling of lipid storage components in the yeast 9th Yeast Lipid Conference, Berlin, Germany, 21-23 May 2009 3. G. Daum, T. Czabany, A. Wagner, K.H. Grillitsch, M. Connerth and S. Rajakumari Turnover of neutral lipids and channeling of lipid storage components in the yeast 27 th ISSY: Pasteur’s legacy – Yeast for Health and Biotechnologies, Paris, France, 26-29 August 2009 22
Publications 1. Wagner, A., Grillitsch, K., Leitner, E. and Daum, G. Mobilization of steryl esters from lipid particles of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta 1791 (2009) 118-124 2. Schuiki, I., and Daum, G. Phosphatidylserine decarboxylases, key enzymes of lipid metabolism IUBMB Life 61 (2009) 151-162 3. Wriessnegger, T., Leitner, E., Belegratis, M. R., Ingolic, E. and Daum, G. Lipid analysis of mitochondrial membranes from the yeast Pichia pastoris. Biochim. Biophys. Acta 1791 (2009) 166-172 4. Rosenberger, S., Connerth, M., Zellnig, G. and Daum, G. Phosphatidylethanolamine synthesized by three different pathways is supplied to peroxisomes of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta 1791 (2009) 379-387 5. Wriessnegger, T, Sunga , A. J., Cregg J. M. and Daum, G. Identification of phosphatidylserine decarboxylases 1 and 2 from Pichia pastoris FEMS Yeast Res. 9 (2009) 911-922 6. Ghosh, A.K., Chauhan, N., Rajakumari, S., Daum, G. and Rajasekharan, R. At4g24160, A Soluble Acyl-Coenzyme Dependent Lysophosphatidic Acid Acyltransferase Plant Physiol. 151 (2009) 869-881 7. Connerth, M., Grillitsch, K., Köfeler, H. and Daum, G. Analysis of Lipid Particles from Yeast Methods Mol. Biol. 579 (2009) 359-374 8. Lin, M., Grillitsch, K., Daum, G., Just, U. and Höfken, T. Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae. FEBS J. 276 (2009) 7253-7264 9. Rajakumari, S. and Daum, G. Janus-faced enzymes yeast Tgl3p and Tgl5p catalyze lipase and acyltransferase reactions Mol. Biol. Cell (2009) in press 10. Schuiki, I., Schnabl, M., Czabany, T., Hrastnik, C. and Daum, G. Phosphatidylethanolamine synthesized by four different pathways is supplied to the plasma membrane of the yeast Saccharomyces cerevisiae. Biochim. Biophys. Acta (2009) in press 11. Spanova, M., Czabany, T., Zellnig, G., Leitner, E., Hapala, I. and Daum, G. Effect of lipid particle biogenesis on the subcellular distribution of squalene in the yeast Saccharomyces cerevisiae. J. Bio. Chem. (2009) in press Award Sona Rajakumari BBA Young Speaker Award, 50th International Conference on Bioscience of Lipids (ICBL), Regensburg, Germany, September 2009 23
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Publications<br />
1. Wagner, A., Grillitsch, K., Leitner, E. and Daum, G.<br />
Mobilization <strong>of</strong> steryl esters from lipid particles <strong>of</strong> <strong>the</strong> yeast Saccharomyces cerevisiae.<br />
Biochim. Biophys. Acta 1791 (2009) 118-124<br />
2. Schuiki, I., and Daum, G.<br />
Phosphatidylserine decarboxylases, key enzymes <strong>of</strong> lipid metabolism<br />
IUBMB Life 61 (2009) 151-162<br />
3. Wriessnegger, T., Leitner, E., Belegratis, M. R., Ingolic, E. and Daum, G.<br />
Lipid analysis <strong>of</strong> mitochondrial membranes from <strong>the</strong> yeast Pichia pastoris.<br />
Biochim. Biophys. Acta 1791 (2009) 166-172<br />
4. Rosenberger, S., Connerth, M., Zellnig, G. and Daum, G.<br />
Phosphatidylethanolamine syn<strong>the</strong>sized by three different pathways is supplied to<br />
peroxisomes <strong>of</strong> <strong>the</strong> yeast Saccharomyces cerevisiae.<br />
Biochim. Biophys. Acta 1791 (2009) 379-387<br />
5. Wriessnegger, T, Sunga , A. J., Cregg J. M. and Daum, G.<br />
Identification <strong>of</strong> phosphatidylserine decarboxylases 1 and 2 from Pichia pastoris<br />
FEMS Yeast Res. 9 (2009) 911-922<br />
6. Ghosh, A.K., Chauhan, N., Rajakumari, S., Daum, G. and Rajasekharan, R.<br />
At4g24160, A Soluble Acyl-Coenzyme Dependent Lysophosphatidic Acid<br />
Acyltransferase<br />
Plant Physiol. 151 (2009) 869-881<br />
7. Connerth, M., Grillitsch, K., Köfeler, H. and Daum, G.<br />
Analysis <strong>of</strong> Lipid Particles from Yeast<br />
Methods Mol. Biol. 579 (2009) 359-374<br />
8. Lin, M., Grillitsch, K., Daum, G., Just, U. and Höfken, T.<br />
Modulation <strong>of</strong> sterol homeostasis by <strong>the</strong> Cdc42p effectors Cla4p and Ste20p in <strong>the</strong> yeast<br />
Saccharomyces cerevisiae.<br />
FEBS J. 276 (2009) 7253-7264<br />
9. Rajakumari, S. and Daum, G.<br />
Janus-faced enzymes yeast Tgl3p and Tgl5p catalyze lipase and acyltransferase reactions<br />
Mol. Biol. Cell (2009) in press<br />
10. Schuiki, I., Schnabl, M., Czabany, T., Hrastnik, C. and Daum, G.<br />
Phosphatidylethanolamine syn<strong>the</strong>sized by four different pathways is supplied to <strong>the</strong><br />
plasma membrane <strong>of</strong> <strong>the</strong> yeast Saccharomyces cerevisiae.<br />
Biochim. Biophys. Acta (2009) in press<br />
11. Spanova, M., Czabany, T., Zellnig, G., Leitner, E., Hapala, I. and Daum, G.<br />
Effect <strong>of</strong> lipid particle biogenesis on <strong>the</strong> subcellular distribution <strong>of</strong> squalene in <strong>the</strong> yeast<br />
Saccharomyces cerevisiae.<br />
J. Bio. Chem. (2009) in press<br />
Award<br />
Sona Rajakumari<br />
BBA Young Speaker Award, 50th International Conference on Bioscience <strong>of</strong> Lipids (ICBL),<br />
Regensburg, Germany, September 2009<br />
23
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