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continued from part 1 - Controller General of Patents, Designs, and ...

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(12) PATENT APPLICATION PUBLICATION (21) Application No.6263/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :17/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS"<br />

(71)Name <strong>of</strong> Applicant :<br />

1)NOVARTIS AG<br />

Address <strong>of</strong> Applicant :LICHTSTRASSE 35, CH-4056<br />

BASEL, SWITZERLAND Switzerl<strong>and</strong><br />

(72)Name <strong>of</strong> Inventor :<br />

1)BURGER MATTHEW<br />

2)NI ZHI-JIE<br />

3)PECCHI SABINA<br />

4)ATALLAH GORDANA<br />

(51) International classification :C07D 401/04<br />

5)BARTULIS SARAH<br />

(31) Priority Document No :60/760,789<br />

6)FRAZIER KELLY<br />

(32) Priority Date :20/01/2006<br />

7)SMITH AARON<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

8)VERHAGEN JOELLE<br />

(86) International Application No :PCT/US2007/001708<br />

9)ZHANG YANCHEN<br />

Filing Date<br />

:22/01/2007<br />

10)WAGMAN ALLAN<br />

(87) International Publication No :WO 2007/084786<br />

11)NG SIMON<br />

(61) Patent <strong>of</strong> Addition to Application<br />

:NA<br />

12)PFISTER KEITH<br />

Number<br />

:NA<br />

13)POON DANIEL<br />

Filing Date<br />

14)LOUIE ALICIA<br />

(62) Divisional to Application Number :NA<br />

15)PICK TERESA<br />

Filing Date<br />

:NA<br />

16)BARSANTI PAUL<br />

17)IWANOWICZ EDWIN<br />

18)FANTL WENDY<br />

19)HENDRICTION THOMAS<br />

20)KNAPP MARK<br />

21)MERITT HANNE<br />

22)VOLIVA CHARLES<br />

23)WIESMANN MARION<br />

24)XIN XIAHUA<br />

(57) Abstract :<br />

Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutical acceptable salts, <strong>and</strong> prodrugs there<strong>of</strong> ; compositions<br />

<strong>of</strong> the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically<br />

acceptable carrier; <strong>and</strong> uses <strong>of</strong> the new compounds, either alone or in combination with at least one additional therapeutic agent, in the<br />

prophylaxis or treatment <strong>of</strong> proliferative diseases characterized by the abnormal activity <strong>of</strong> growth factors, protein serine/threonine<br />

kinases, <strong>and</strong> phospholipid kinases.<br />

No. <strong>of</strong> Pages : 255 No. <strong>of</strong> Claims : 54<br />

The Patent Office Journal 24/10/2008 25821

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