continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6330/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :18/07/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : ANTI-ILT7 ANTIBODY
(51) International classification :C07K 16/28 (71)Name of Applicant :
(31) Priority Document No :2005-366465 1)SBI BIOTECH CO. LTD
(32) Priority Date :20/12/2005
Address of Applicant :SHIROKANEDAI ST BUILDING 8F,
(33) Name of priority country :Japan
4-7-4, SHIROKANEDAI, MINATO-KU, TOKYO 108-0071(JP)
(86) International Application No :PCT/JP2006/325391 Japan
Filing Date
:20/12/2006 (72)Name of Inventor :
(87) International Publication No :WO 2007/072866 1)KAMOGAWA, YUMIKO
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
2)CHO, MINKWON
3)ARAI, NAOKO
4)ISHIDA,KOJI
(62) Divisional to Application Number :NA
Filing Date
:NA
(57) Abstract :
An antibody binding to IPC was obtained by using an animal cell in which a cell membrane protein associatable with ILT7 was coexpressed
as an immunogen. The antibody of the invention has a high specificity which allows immunological distinction between
other ILT family molecules and ILT7. The anti-ILT7 antibody of the invention bound to IPC and inhibited the activity thereof . With
the anti-ILT7 antibody of the invention, the IPC activity can be inhibited and an interferon-related disease can be treated or prevented.
ILT7 expression is maintained even in IPC in the presence of IFNα. Therefore, an inhibitory action of IPC activity by the anti-ILT7
antibody can be expected even in an autoimmune disease patient with an increased production of IFNα.
No. of Pages : 150 No. of Claims : 31
The Patent Office Journal 24/10/2008 25805