continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6291/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :18/07/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : "ALLELIC EXCLUSION"
(51) International classification :C07K 16/00 (71)Name of Applicant :
(31) Priority Document No :0601511.9
1)ERASMUS UNIVERSITY MEDICAL CENTER
(32) Priority Date :25/01/2006 ROTTERDAM
(33) Name of priority country :U.K.
Address of Applicant :P.O. BOX 2040, NL-3000 CA
(86) International Application No :PCT/IB2007/001491 ROTTERDAM, NETHERLANDS. Netherlands
Filing Date
:25/01/2007 (72)Name of Inventor :
(87) International Publication No :WO 2007/096779 1)FRANKLIN GERARDUS GROSVELD
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
2)RICHARD WILHELM JANSSENS
(62) Divisional to Application Number :NA
Filing Date
:NA
(57) Abstract :
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal.
In particular, the present invention relates to a method for the production of a VH heavy chain-only antibody in a transgenic nonhuman
mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal.
No. of Pages : 70 No. of Claims : 34
The Patent Office Journal 24/10/2008 25799