continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6792/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :07/08/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : "PYRROLO [3,2-C] PYRIDINE-4-ONE 2-INDOLINONE PROTEIN KINASE INHIBITORS"
(51) International classification :C07D 47/04 (71)Name of Applicant :
(31) Priority Document No :200610003229.6 1)SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD.
(32) Priority Date :27/01/2006
Address of Applicant :NO.279 WENJING ROAD,
(33) Name of priority country :China
MINHANG DISTRICT, SHANGHAI 200245, CHINA. China
(86) International Application No :PCT/CN2007/000256 (72)Name of Inventor :
Filing Date
:24/01/2007
1)TANG, PENG CHO
(87) International Publication No :WO 2007/085188 2)SU, YIDONG
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
3)ZHANG, LEI
4)XIAO, LU
(62) Divisional to Application Number :NA
Filing Date
:NA
(57) Abstract :
The present invention relates to pyrrolo[3,2-c]pyridine-4-one 2-indolinone compounds of Formula (I) and their pharmaceutically
acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8 X , Y and &mldr,: have the meaning cited in the specification. Also
disclosed are the pharmaceutical compositions containing the foregoing compounds, methods for the preparation and pharmaceutical
use thereof, particularly as protein kinase inhibitors.Formula (I)
No. of Pages : 217 No. of Claims : 32
The Patent Office Journal 24/10/2008 26233