continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6789/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :06/08/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : "HEPATITIS C VIRUS NON STRUCTURAL FUSION PROTEIN"
(51) International classification :A61K 39/29 (71)Name of Applicant :
(31) Priority Document No :06360006.8
1)TRANSGENE S.A.
(32) Priority Date :09/03/2006
Address of Applicant :11, RUE DE MOLSHEIM, F-67082
(33) Name of priority country
:EUROPEAN
UNION
STRASBOURG CEDEX FRANCE. France
(72)Name of Inventor :
(86) International Application No :PCT/EP2007/001922 1)FOURNILLEIR ANNE
Filing Date
:06/03/2007
2)INCHAUSPE GENEVIEVE
(87) International Publication No :WO 2007/101657 3)CHATER LAURENCE
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
4)PENIN FRANCOIS
(62) Divisional to Application Number :NA
Filing Date
:NA
(57) Abstract :
The present invention relates to an isolated fusion protein comprising at least three NS polypeptides originating from a hepatitis C
virus which are configured in said fusion protein in an order which is distinct of the order in which they appear in the native
configuration. The present invention also relates to a nucleic acid molecule encoding such a fusion protein and a vector comprising
such a nucleic acid molecule. The present invention also provides infectious viral particles and host cells comprising such a nucleic
acid molecule or such a vector. The present invention also relates to a method for recombinantly producing such a fusion protein.
Finally, the present invention also provides a pharmaceutical composition comprising such a fusion protein, a nucleic acid molecule, a
vector, infectious viral particles and a host cell as well as the therapeutic use thereof for treating or preventing HCV infections, HCVassociated
diseases and pathologic conditions as well as a method of inducing or stimulating an immune response against HCV in a
host organism.
No. of Pages : 108 No. of Claims : 36
The Patent Office Journal 24/10/2008 26214