continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6774/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :06/08/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : "PIPERAZINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY"
(51) International classification :C07D 213/56 (71)Name of Applicant :
(31) Priority Document No :60/763,051 1)BRISTOL-MYERS SQUIBB COMPANY,
(32) Priority Date :27/01/2006
Address of Applicant :ROUTE 206 AND PROVINCE LINE
(33) Name of priority country :U.S.A.
ROAD, PRINCETON, NEW JERSEY 08543-4000, USA. U.S.A.
(86) International Application No
:PCT/US07/061014 (72)Name of Inventor :
Filing Date
:25/01/2007 1)PERCY H. CARTER,
(87) International Publication No :WO 2007/087585 2)CULLEN L. CAVALLARO
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
3)GEORGE V. DE LUCCA
(62) Divisional to Application Number :NA
Filing Date
:NA
(57) Abstract :
The present application describes modulators of MIP-lα of formula (I): or stereoisomers or pharmaceutically acceptable salts thereof,
wherein m, T, W, R1, R4,, R5, R5a and R5b are as defined herein. In addition, methods of treating and preventing inflammatory
diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and atherosclerosis
using said modulators are disclosed.
No. of Pages : 185 No. of Claims : 23
The Patent Office Journal 24/10/2008 26184