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(12) PATENT APPLICATION PUBLICATION (21) Application No.6729/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :04/08/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "METHODS AND COMPOSITIONS RELATED TO IMPROVING PROPERTIES OF<br />

PHARMACOLOGICAL AGENT TARGETING NERVOUS SYSTEM"<br />

(51) International classification :A61K 38/17 (71)Name <strong>of</strong> Applicant :<br />

(31) Priority Document No :60/757,047<br />

1)UNIVERSITY OF UTAH RESEARCH FOUNDATION<br />

(32) Priority Date :05/01/2006<br />

Address <strong>of</strong> Applicant :615 ARAPEEN DRIVE, SUITE 310,<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

SALT LAKE CITY, UT 84108 U.S.A. U.S.A.<br />

(86) International Application No :PCT/US2007/000261 (72)Name <strong>of</strong> Inventor :<br />

Filing Date<br />

:05/01/2007<br />

1)BULAJ GRZEGORZ<br />

(87) International Publication No :WO 2007/081792 2)WHITE STEVE H.<br />

(61) Patent <strong>of</strong> Addition to Application<br />

Number<br />

Filing Date<br />

:NA<br />

:NA<br />

(62) Divisional to Application Number :NA<br />

Filing Date<br />

:NA<br />

(57) Abstract :<br />

Disclosed are compositions <strong>and</strong> methods related to improving pharmacological properties <strong>of</strong> bioactive compounds targeting nervous<br />

system. An isolated polypeptide comprising SEQ ID NO: 3, an amino acid sequence at least about 90% identical to the amino acid<br />

sequence <strong>of</strong> SEQ ID NO: 3, or the amino acid sequence <strong>of</strong> SEQ ID NO: 3 having one or more conservative amino acid substitutions.<br />

No. <strong>of</strong> Pages : 159 No. <strong>of</strong> Claims : 21<br />

The Patent Office Journal 24/10/2008 26181

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