continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6665/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :31/07/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : "COMPOSITIONS AND METHODS FOR COMBINATION ANTIVIRAL THERAPY"
(51) International classification :A61K 31/675 (71)Name of Applicant :
(31) Priority Document No :60/440,308
1)GILEAD SCIENCES,INC
(32) Priority Date :14/01/2003
Address of Applicant :333 LAKESIDE DRIVE,FOSTER
(33) Name of priority country :U.S.A.
CITY,CA 94404,U.S.A. U.S.A.
(86) International Application No :PCT/US2005/000832 (72)Name of Inventor :
Filing Date
:13/01/2004
1)DAHL,TERRENCE C.
(87) International Publication No :WO 2004/064845 2)MENNING,MARK,M.
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
3)OLIYAI,REZA
(62) Divisional to Application Number :3383/DELNP/2005
Filed on
:29/07/2005
(57) Abstract :
The present invention relates to therapeutic combinations of [2-(6-amino- purin-9 yl)-l-methyl-ethoxymethyl]-phosphonic acid
diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R, 5S, cis)-4-amino-5-fluoro-l-(2 hydroxymethy
1-1,3-oxathiolan-5-yl)-(lH)-pyrimidin-2-one (emtricitabine, Emtriva„, (-)-cis FTC) and their physiologically functional derivatives.
The combinations may be useful in the treatment of HIV infections, including infections with HIV mutants bearing resistance to
nucleoside and/or non-nucleoside inhibitors. The present invention is also concerned with pharmaceutical compositions and
formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives,
as well as therapeutic methods of use of those compositions and formulations.
No. of Pages : 53 No. of Claims : 19
The Patent Office Journal 24/10/2008 26134