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(12) PATENT APPLICATION PUBLICATION (21) Application No.6610/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :30/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO DEGENERATIVE<br />

DISEASES"<br />

(71)Name <strong>of</strong> Applicant :<br />

1)NV REMYND<br />

(51) International classification :A61K 31/496<br />

Address <strong>of</strong> Applicant :MINDERBROEDERSSTRAAT 12 B-<br />

(31) Priority Document No :0602335.2<br />

3000 LEUVEN, BELGIUM Belgium<br />

(32) Priority Date :07/02/2006<br />

(72)Name <strong>of</strong> Inventor :<br />

(33) Name <strong>of</strong> priority country :U.K.<br />

1)GRIFFIOEN, GERARD<br />

(86) International Application No :PCT/EP2007/001022<br />

2)COUPET, KRISTEL, MARIE EDITH<br />

Filing Date<br />

:07/02/2007<br />

3)DUHAMEL, HEIN, ROGER<br />

(87) International Publication No :WO 2007/090617<br />

4)WERA, STEFAAN<br />

(61) Patent <strong>of</strong> Addition to Application<br />

:NA<br />

5)GOMME, ELLEN<br />

Number<br />

:NA<br />

6)VAN DAMME, NELE<br />

Filing Date<br />

7)VAN DER AUWERA, INGRID<br />

(62) Divisional to Application Number :NA<br />

8)LOX, MARLEEN<br />

Filing Date<br />

:NA<br />

9)VAN DOOREN, TOM<br />

10)DECRUY, TINE<br />

(57) Abstract :<br />

This invention provides specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment <strong>of</strong> an a-synucleopathy such as<br />

Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease,<br />

Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy <strong>and</strong> Alzheimer's disease.<br />

No. <strong>of</strong> Pages : 114 No. <strong>of</strong> Claims : 41<br />

The Patent Office Journal 24/10/2008 26088

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