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(12) PATENT APPLICATION PUBLICATION (21) Application No.6557/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :28/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "A PROCESS FOR PREPARATION OF RACEMIC NEBIVOLOL"<br />

(51) International classification : C07D 311/58 (71)Name <strong>of</strong> Applicant :<br />

(31) Priority Document No :11/319,287<br />

1)CIMEX PHARMA AG<br />

(32) Priority Date :28/12/2005<br />

Address <strong>of</strong> Applicant :BIRSWEG2, CH-4253 LIESBERG<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

(BL) SWITZERLAND. Switzerl<strong>and</strong><br />

(86) International Application No :PCT/IB2006/004280 2)UNIVERSITY OF ZURICH<br />

Filing Date<br />

:28/12/2006 (72)Name <strong>of</strong> Inventor :<br />

(87) International Publication No :WO 2008/010022 1)BADER THOMAS<br />

(61) Patent <strong>of</strong> Addition to Application<br />

Number<br />

Filing Date<br />

:NA<br />

:NA<br />

2)STUTZ ALFRED<br />

3)HOFMEIER HARALD<br />

4)BICHSEL HANS-ULRICH<br />

(62) Divisional to Application Number :NA<br />

Filing Date<br />

:NA<br />

(57) Abstract :<br />

A process <strong>of</strong> making racemic [2S*[R*[R*[R*]]]] <strong>and</strong> [2R*[S*[S*[S*]]]]-(+)α,α'- [iminobis(methylene)]bis[6-fluoro-3,4-dihy- dro-<br />

2H-l-benzopyran-2-methanol] <strong>of</strong> the compound <strong>of</strong> the formula (I) <strong>and</strong> its pure [2S*[R*[R*[R*]]]]-<strong>and</strong> [2R*[S*[S*[S*]]]]- enantiomer<br />

compounds <strong>and</strong> pharmaceutically acceptable salts there<strong>of</strong>.<br />

No. <strong>of</strong> Pages : 122 No. <strong>of</strong> Claims : 106<br />

The Patent Office Journal 24/10/2008 26071

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