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(12) PATENT APPLICATION PUBLICATION (21) Application No.6556/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :28/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF DISEASE"<br />

(51) International classification :A61K 31/55 (71)Name <strong>of</strong> Applicant :<br />

(31) Priority Document No :60/755,632<br />

1)IMMUPHARMA FRANCE SA<br />

(32) Priority Date :29/12/2005<br />

Address <strong>of</strong> Applicant :TECHNOPOLE, 40, RUE MARC<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

SEGUIN, BP 2118, France<br />

(86) International Application No :PCT/EP2006/070257 (72)Name <strong>of</strong> Inventor :<br />

Filing Date<br />

:28/12/2006<br />

1)GUICHARD GILLES<br />

(87) International Publication No :WO 2007/074170 2)GERSANDE LENA<br />

(61) Patent <strong>of</strong> Addition to Application<br />

Number<br />

Filing Date<br />

:NA<br />

:NA<br />

3)LALLEMAND ELIETTE<br />

4)RENIA LAURENT<br />

(62) Divisional to Application Number :NA<br />

Filing Date<br />

:NA<br />

(57) Abstract :<br />

The present invention relates to various novel substituted dipeptide derived nitrogen-containing heterocyclic compounds, their<br />

pharmaceutically acceptable salt derivatives, <strong>and</strong> their methods <strong>of</strong> use. In one aspect the present invention relates to compositions <strong>and</strong><br />

methods for the treatment <strong>and</strong> prevention <strong>of</strong> disease in a mammal comprising administering the compounds <strong>of</strong> the invention in a<br />

pharmaceutically acceptable form to a mammal. In <strong>part</strong>icular, the invention relates to medicaments comprising various novel<br />

substituted dipeptide derived nitrogen- containing heterocyclic compounds <strong>and</strong> pharmaceutically acceptable salt derivatives <strong>and</strong><br />

methods for administration to a mammal for the treatment <strong>and</strong> prevention <strong>of</strong> malarial diseases. The compounds <strong>of</strong> the invention may<br />

optionally be administered with at least one pharmaceutically acceptable excipient, another biologically active agent or a combination<br />

there<strong>of</strong>.<br />

No. <strong>of</strong> Pages : 40 No. <strong>of</strong> Claims : 19<br />

The Patent Office Journal 24/10/2008 26070

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