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(12) PATENT APPLICATION PUBLICATION (21) Application No.6277/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :18/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "DNT-BENZENESULFONATE AND METHODS OF PREPARATION THEREOF"<br />

(51) International classification :C07D 333/20 (71)Name <strong>of</strong> Applicant :<br />

(31) Priority Document No :60/761,562<br />

1)TEVA PHARMACEUTICAL INDUSTRIES LTD.<br />

(32) Priority Date :23/01/2006<br />

Address <strong>of</strong> Applicant :5 BASEL STREET, P.O. BOX 3190,<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

PETAH TIQVA 49131, ISRAEL, Israel<br />

(86) International Application No :PCT/US2006/036976 (72)Name <strong>of</strong> Inventor :<br />

Filing Date<br />

:21/09/2006<br />

1)MILI ABRAMOV<br />

(87) International Publication No :WO 2007/084194 2)SANTIAGO INI<br />

(61) Patent <strong>of</strong> Addition to Application<br />

Number<br />

Filing Date<br />

:NA<br />

:NA<br />

3)TAMAS KOLTAI<br />

(62) Divisional to Application Number :NA<br />

Filing Date<br />

:NA<br />

(57) Abstract :<br />

(S)-N,N-Dimethyl-3-(l-naphthalenyloxy)-3-(2-thienyl)propanamine benzenesulfonate (DNT-benzenesulfonate) <strong>and</strong> polymorphs <strong>of</strong><br />

DNT-benzenesulfonate, compositions <strong>of</strong> DNT-benzenesulfonate <strong>and</strong> its polymorphs, processes for the preparation <strong>of</strong> DNTbenzenesulfonate<br />

<strong>and</strong> its polymorphs, <strong>and</strong> processes for the preparation <strong>of</strong> duloxetine hydrochloride <strong>from</strong> DNT-benzenesulfonate are<br />

provided.<br />

No. <strong>of</strong> Pages : 12 No. <strong>of</strong> Claims : 17<br />

The Patent Office Journal 24/10/2008 25761

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