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(12) PATENT APPLICATION PUBLICATION (21) Application No.6474/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :24/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "NOGO RECEPTOR ANTAGONISTS"<br />

(71)Name <strong>of</strong> Applicant :<br />

1)BIOGEN IDEC MA INC.<br />

(51) International classification :C07K 7/64<br />

Address <strong>of</strong> Applicant :14 CAMBRIDGE CENTER,<br />

(31) Priority Document No :60/762,487<br />

CAMBRIDGE, MA 02142, USA. U.S.A.<br />

(32) Priority Date :27/01/2006<br />

(72)Name <strong>of</strong> Inventor :<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

1)DANIEL H.S. LEE<br />

(86) International Application No<br />

:PCT/US07/002199<br />

2)DINGYI WEN<br />

Filing Date<br />

:26/01/2007<br />

3)BLAKE R. PEPINSKY<br />

(87) International Publication No :WO 2007/089601<br />

4)JANE K. RELTON<br />

(61) Patent <strong>of</strong> Addition to Application<br />

:NA<br />

5)XINZHONG WANG<br />

Number<br />

:NA<br />

6)ALEXEY LUGOVSKOY<br />

Filing Date<br />

7)WERNER MEIER<br />

(62) Divisional to Application Number :NA<br />

8)ELLEN A. GARBER<br />

Filing Date<br />

:NA<br />

9)LAURA SILVIAN<br />

10)PAUL H. WEINREB<br />

(57) Abstract :<br />

Disclosed are immunogenic Nogo receptor-I polypeptides, Nogo receptor-I antibodies, antigen-binding fragments there<strong>of</strong>, soluble<br />

Nogo receptors <strong>and</strong> fusion proteins there<strong>of</strong> <strong>and</strong> nucleic acids encoding the same. Also disclosed are Nogo receptor antagonist<br />

polynucleotides. Also disclosed are compositions comprising, <strong>and</strong> methods for making <strong>and</strong> using, such Nogo receptor antibodies,<br />

antigen-binding fragments there<strong>of</strong>, soluble Nogo receptors <strong>and</strong> fusion proteins there<strong>of</strong>, nucleic acids encoding the same <strong>and</strong> antagonist<br />

polynucleotide.<br />

No. <strong>of</strong> Pages : 180 No. <strong>of</strong> Claims : 127<br />

The Patent Office Journal 24/10/2008 25942

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