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continued from part 1 - Controller General of Patents, Designs, and ...

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(12) PATENT APPLICATION PUBLICATION (21) Application No.6423/DELNP/2008 A<br />

(19) INDIA<br />

(22) Date <strong>of</strong> filing <strong>of</strong> Application :22/07/2008 (43) Publication Date : 24/10/2008<br />

(54) Title <strong>of</strong> the invention : "INHIBITORS OF E1 ACTIVATING ENZYME"<br />

(51) International classification :C07D 471/04 (71)Name <strong>of</strong> Applicant :<br />

(31) Priority Document No :60/764,487<br />

1)MILLENNIUM PHARMACEUTICAL, INC.<br />

(32) Priority Date :02/02/2006<br />

Address <strong>of</strong> Applicant :40 LANDSDOWNE STREET,<br />

(33) Name <strong>of</strong> priority country :U.S.A.<br />

CAMBRIDGE, MA 02139, UNITED STATES OF AMERICA.<br />

(86) International Application No :PCT/US2007/002560 U.S.A.<br />

Filing Date<br />

:31/01/2007 (72)Name <strong>of</strong> Inventor :<br />

(87) International Publication No :WO 2007/092213 1)STEPHEN P. LANGSTON<br />

(61) Patent <strong>of</strong> Addition to Application<br />

Number<br />

Filing Date<br />

:NA<br />

:NA<br />

2)EDWARD J. OLHAWA<br />

3)STEPAN VYSKOCIL<br />

(62) Divisional to Application Number :NA<br />

Filing Date<br />

:NA<br />

(57) Abstract :<br />

This invention relates to compounds that inhibit El activating enzymes, pharmaceutical compositions comprising the compounds, <strong>and</strong><br />

methods <strong>of</strong> using the compounds. The compounds are useful for treating disorders, <strong>part</strong>icularly cell proliferation disorders, including<br />

cancers, inflammatory <strong>and</strong> neur ode generative disorders; <strong>and</strong> inflammation associated with infection <strong>and</strong> cachexia.<br />

No. <strong>of</strong> Pages : 180 No. <strong>of</strong> Claims : 33<br />

The Patent Office Journal 24/10/2008 25918

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