continued from part 1 - Controller General of Patents, Designs, and ...

(12) PATENT APPLICATION PUBLICATION (21) Application No.6377/DELNP/2008 A
(19) INDIA
(22) Date of filing of Application :21/07/2008 (43) Publication Date : 24/10/2008
(54) Title of the invention : "STABLIZED PHARMACEUTICAL COMPOSITION"
(51) International classification :A61K 31/4196 (71)Name of Applicant :
(31) Priority Document No :2006-045569 1)EISAI R&D MANAGEMENT CO.,LTD.
(32) Priority Date :22/02/2006
Address of Applicant :6-10,KOISHIKAWA 4-
(33) Name of priority country :Japan
CHOME,BUNKYO-KU,TOKYO 112-8088 JAPAN. Japan
(86) International Application No :PCT/JP2007/053246 (72)Name of Inventor :
Filing Date
:22/02/2007
1)ISHIMOTO HAYATO
(87) International Publication No :WO 2007/097386 2)HARADA TSUTOMU
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
3)OMAE HIROSHI
(62) Divisional to Application Number :NA
Filing Date
:NA
(57) Abstract :
It is an object of the present invention to provide a pharmaceutical composition containing a stable azole-based compound, which is
useful as an antifungal agent. According to the present invention, the above-mentioned object can be achieved by adding magnesium
hydroxide carbonate, triethylamine, arginine, or another such basic substance to an azole-based compound that is unstable in acids.
The above-mentioned pharmaceutical composition is stable enough that the compound will not degrade if the temperature, humidity,
or other such conditions should change during production or storage. Also, this composition is useful as a therapeutic agent for deep
mycoses because systemic administration is possible by applying it to an oral agent or an injection.
No. of Pages : 34 No. of Claims : 17
The Patent Office Journal 24/10/2008 25861