Hepatitis E: What’s New?
Diagnostic tests for HEV IgM anti-HEV Early phase of clinical illness Sensitivity 80-90% Specificity 92% IgG anti-HEV Appears shortly after IgM Persist as long as 14 yrs after acute illness HEV-RNA Appear early in stool Short-lived in acute infection Two real-time PCR assays
Centers for Disease Control and Prevention. www.cdc.gov/hepatitis/index.htm
- Page 2 and 3: HEPATITIS E: WHAT’S NEW? Naglaa Z
- Page 4 and 5: Known Facts: HEV ■ 20 million HEV
- Page 6 and 7: Geographical Distribution of HEV Eg
- Page 8 and 9: HEV Genotypes Four genotypes/24 sub
- Page 10 and 11: Modes of HEV Transmission Fecal-ora
- Page 12 and 13: Clinical Picture of HEV
- Page 14 and 15: Complications of Acute HEV Acute Li
- Page 16 and 17: Clinical Picture: Complications Acu
- Page 18 and 19: Chronic Hepatitis E Persistently el
- Page 20 and 21: Chronic Hepatitis E Other Immunosup
- Page 24 and 25: HEV Diagnosis Acute HEV Chronic HEV
- Page 26 and 27: Treatment of HEV Acute HEV Signific
- Page 28 and 29: Treatment of Chronic HEV Reduction
- Page 30 and 31: Response to Antiviral Therapy Stool
- Page 34 and 35: Treatment of HEV: Future Therapy
- Page 36 and 37: Randomized trial in China, 112,604
Centers for Disease Control and Prevention. www.cdc.gov/hepatitis/index.htm