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Diagnostic tests for HEV<br />
IgM anti-HEV<br />
Early phase of clinical illness<br />
Sensitivity 80-90% Specificity 92%<br />
IgG anti-HEV<br />
Appears shortly after IgM<br />
Persist as long as 14 yrs after acute illness<br />
HEV-RNA<br />
Appear early in stool<br />
Short-lived in acute infection<br />
Two real-time PCR assays