Where are we on the path to eliminate hepatitis C virus ?
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Nearly Every<strong>on</strong>e With HCV Can Now Be Treated<br />
Successfully<br />
• Very high SVR rates; <strong>the</strong>rapies highly <strong>to</strong>lerable<br />
• All-oral <strong>the</strong>rapy for almost every pt<br />
• Treatment generally just 12 wks<br />
100<br />
80<br />
60<br />
40<br />
Standard<br />
Interfer<strong>on</strong><br />
1991<br />
Ribavirin<br />
1998<br />
34<br />
Peginterfer<strong>on</strong><br />
2001<br />
42 39<br />
55<br />
Direct-Acting<br />
Antivirals<br />
2011<br />
70+<br />
2013<br />
90+<br />
All-Oral<br />
Therapy<br />
Current<br />
95+<br />
20<br />
0<br />
6<br />
IFN<br />
6 Mos<br />
16<br />
IFN<br />
12 Mos<br />
IFN/RBV<br />
6 Mos<br />
IFN/RBV<br />
12 Mos<br />
PegIFN<br />
12 Mos<br />
PegIFN/<br />
RBV<br />
12 Mos<br />
PegIFN/<br />
RBV +<br />
DAA<br />
DAA +<br />
RBV ±<br />
PegIFN<br />
All–Oral<br />
DAA±<br />
RBV<br />
7
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