Where are we on the path to eliminate hepatitis C virus ?

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06.03.2017 Views

Why HCV Is A Tractable Target For Eradication ? • No known non-human reservoir • There is no latent cellular reservoir • Pharmacologic treatment with direct acting antivirals can truly cure an infected person, treatment-based elimination is an option 5

Barriers To Elimination • Hepatitis C is generally asymptomatic both during the acute and chronic phase. • Heavy concentration of HCV infections in difficult-to reach populations, including people who inject drugs and the homeless, as ong>weong>ll as marginalized groups such as the incarcerated. • The treatment cost is expensive. This expense raises concerns about the feasibility of widespread treatment • A prophylactic vaccine may be an essential missing piece of the effort to eliminate hepatitis C. • Reinfection is a possibility 6

Why HCV Is A Tractable Target For<br />

Eradicati<strong>on</strong> ?<br />

• No known n<strong>on</strong>-human reservoir<br />

• There is no latent cellular reservoir<br />

• Pharmacologic treatment with direct<br />

acting antivirals can truly cure an<br />

infected pers<strong>on</strong>, treatment-based<br />

eliminati<strong>on</strong> is an opti<strong>on</strong><br />

5

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