Where are we on the path to eliminate hepatitis C virus ?

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Control vs. Elimination vs. Eradication ‣Control: Reduction In Prevalence, Morbidity/Mortality Of An Infectious Disease To A Locally Acceptable Level. ‣Elimination: Reduction To Zero Of The Incidence Of Disease Or Infection In A Defined Geographical Area, But Requires Continued Measures To Prevent Re-establishment Of Transmission ‣Eradication: Permanent Reduction To Zero Of The Worldwide Incidence Of Infection, With No Further Control Measures Required WHO 1998 CDC, 1993; Dowdle, 1998. 3
• World Health Organization goal is to eliminate hepatitis C virus (HCV) as a public health threat • Specifically, the goal is dramatic and large scale reductions in new transmissions of HCV, as <strong>we</strong>ll as in the number of people becoming ill and dying from HCV, to a level where HCV no longer represents a major health concern • In numeric terms, the WHO has proposed reductions of 60% in HCV related mortality and 90% in HCV transmission globally and in member countries John W. Ward, Gastroenterology & Hepatology 2016 4
Page 2 and 3: Are we on the path
Page 6 and 7: Why HCV Is A Tractable Target For E
Page 8 and 9: Nearly Everyone With HCV Can Now Be
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Page 12 and 13: Viremic Infections (by Stage) Impac
Page 14 and 15: Focusing on Cirrhosis Rapid reducti
Page 16 and 17: Pts (%) HCV in the US: Gaps in Curr
Page 18 and 19: HCV is not JUST a liver virus ‣Pe
Page 20 and 21: Pts (%) HCV Affects Pts’ Lives No
Page 22 and 23: Treating Everyone ‣Encourages tes
Page 24 and 25: Increasing SVR >90% with increase i
Page 26 and 27: Eliminating HCV Is Everyone’s Job
Page 28 and 29: WHAT needs to be done? 1 • Innova
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Page 32 and 33: Could HCV Be Eliminated Through Ant
Page 34 and 35: Impact Of Prevention On Outcome Of
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Where are we on the path to eliminate hepatitis C virus ?

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