Management of DAAs Failure
If you have failure of plan A in treating a patient with chronic hepatitis C. What's your plan B
If you have failure of plan A in treating a patient with chronic hepatitis C. What's your plan B
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Guidelines <strong>of</strong> the National Treatment Program in Egypt<br />
• Patients who failed previous S<strong>of</strong>osbuvir containing regimen<br />
• Treatment will be with S<strong>of</strong>osbuvir + Daclatasvir + Ribavirin<br />
Or<br />
S<strong>of</strong>osbuvir + ledipasvir +ribavirin<br />
• for 24 weeks.<br />
• The dose <strong>of</strong> ribavirin is 600 mg/day in cirrhotics, A trial should be done to<br />
reach a dose <strong>of</strong> 1000 mg/day based on the patient tolerability
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