DESCRIPTIONS OF MEDICAL FUNGI

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86 Descriptions of Medical Fungi Exophiala dermatitidis (Kano) de Hoog Antifungal Susceptibility: E. dermatitidis (Duarte et al. 2013 and Australian National data); MIC µg/mL. No. 64 AmB 44 1 2 25 16 VORI 44 4 12 20 1 4 2 1 POSA 1 1 ITRA 44 10 13 6 9 4 1 1 E. dermatitidis data from 27 isolates (Fothergill et al. 2009); MIC µg/mL. AmB Range 0.125-1; MIC 90 = 1 VORI Range 0.06-1; MIC 90 = 0.25 ITRA Range
Descriptions of Medical Fungi 87 RG-2 organism. Exophiala jeanselmei complex Exophiala jeanselmei McGinnis & Padhye Morphological Description: Colonies are initially smooth, greenish-grey to black, mucoid and yeast-like, becoming raised and developing tufts of aerial mycelium with age, often becoming dome-shaped and suede-like in texture. Reverse is olivaceousblack. Numerous ellipsoidal, yeast-like, budding cells are usually present, especially in young cultures. Scattered amongst these yeast-like cells are larger, inflated, subglobose to broadly ellipsoidal cells (germinating cells) which give rise to short torulose hyphae that gradually change into unswollen hyphae. Conidia are formed on lateral pegs either arising apically or laterally at right or acute angles from essentially undifferentiated hyphae or from strongly inflated detached conidia. Conidiogenous pegs are 1-3 µm long, slightly tapering and imperceptibly annellate. Conidia are hyaline, smooth, thinwalled, broadly ellipsoidal, 3.2-4.4 x 1.2-2.2 µm, and with inconspicuous basal scars. Cultures grow at 37 O C but not at 40 O C. a 5 µm b 15 µm 5 µm Exophiala jeanselmei complex showing annellides, conidia and conidiogenous pegs (annellides) on (a) yeast-like cells and (b) torulose hyphae. References: de Hoog and Hermanides-Nijhof (1977), de Hoog (1977, 1985), McGinnis and Padhye (1977), McGinnis (1978b, 1980), Domsch et al. (1980), Nishimura and Miyaji (1983), Matsumoto et al. (1987), Dixon and Polak-Wyss (1991), Badali et al. 2010, de Hoog et al. (2000, 2003, 2006, 2015).
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DESCRIPTIONS OF MEDICAL FUNGI

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