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DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi 65<br />

Coniochaeta hoffmannii (J.F.H. Beyma) Z.U. Khan, Gené & Guarro<br />

Note: Coniochaeta and Phialemonium species are poorly differentiated morphologically,<br />

and are difficult to identify. They may also be confused with poorly sporulating Fusarium<br />

or Acremonium species.<br />

Molecular Identification: Khan et al. (2013) used a combined sequence data set of<br />

the ITS region, D1/D2, actin and β-tubulin genes to resolve the unique phylogenetic<br />

status of this species.<br />

References: de Hoog (1983), de Hoog et al. (2000, 2015), Perdomo et al. (2011b),<br />

Khan et al. (2013).<br />

a<br />

b<br />

10 µm<br />

b<br />

10 µm<br />

Coniochaeta hoffmannii (a) culture, (b) hyphae with small collarettes and conidia.<br />

Antifungal Susceptibility: Coniochaeta hoffmannii very limited data (McGinnis and<br />

Pasarell 1998a, Perdomo et al. 2011b and Australian National data); MIC µg/mL.<br />

Antifungal Range MIC 90<br />

Antifungal Range MIC 90<br />

AmB 0.06-2 2 POSA 0.125-1 1<br />

ITRA 0.06-32 1 VORI 0.25-1 1

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