DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi
Candida glabrata complex
Candida nivariensis Alcoba-Flórez et al.
RG-2 organism.
Culture: Colonies (SDA) white to cream-coloured smooth, glabrous, yeast-like.
Microscopy: Ellipsoidal budding blastoconidia, 3-5 x 1.8-3 µm in size. No pseudohyphae
or chlamydospores produced.
India Ink Preparation: Negative - no capsules present.
Dalmau Plate Culture: No pseudohyphae produced.
Physiological Tests: + Positive, - Negative, v Variable, w Weak, s Slow
Germ Tube - L-Sorbose - L-Arabinose - D-Glucitol -
Fermentation Sucrose - D-Arabinose - α-M-D-glucoside -
Glucose + Maltose - D-Ribose - D-Gluconate +
Galactose - Cellobiose - L-Rhamnose - DL-Lactate -
Sucrose - Trehalose - D-Glucosamine - myo-Inositol -
Maltose - Lactose - N-A-D-glucosamine - 2-K-D-gluconate -
Lactose - Melibiose - Glycerol + D-Glucuronate -
Trehalose Raffinose - Erythritol - Nitrate -
Assimilation Melezitose - Ribitol - Urease -
Glucose + Soluble Starch v Galactitol - 0.1% Cycloheximide -
Galactose - D-Xylose - D-Mannitol - Growth at 40 O C +
C. nivariensis is closely related to C. glabrata and C. bracarensis. These three species
were found to differ by DNA-DNA reassociation experiments, RAPD-typing, AFLPtyping
and D1/D2 and ITS sequence divergence (Alcoba-Flórez et al. 2005, Correia et
al. 2006, Wahyuningsih et al. 2008).
Antifungal Susceptibility: C. nivariensis limited data (Australian National data);
MIC µg/mL.
No 64
AmB 4 1 1 2
FLU 4 1 1 2
VORI 4 2 1 1
POSA 4 1 1 2
ITRA 4 4
ANID 4 1 1 2
MICA 4 2 2
CAS 4 2 2
5FC 4 1 2 1