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DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi 181<br />

Scedosporium aurantiacum Gilgado et al.<br />

Morphological Description: Most isolates produce a light yellow diffusible pigment<br />

on potato dextrose agar after a few days incubation. Conidiogenous cells and<br />

conidia are similar in shape and size to S. apiospermum, and the two can best be<br />

distinguished by genetic analysis. Conidiogenous cells arising from undifferentiated<br />

hyphae are cylindrical to slightly flask-shaped, producing slimy heads of one-celled<br />

, smooth-walled, subhyaline, obovoid or sub-cylindrical conidia. 5-14 x 2-5 um. Erect<br />

synnemata may be present in some isolates, but the teleomorph is unknown. Optimum<br />

temperature for growth 37-40 O C, max 45 O C. RG-2 organism.<br />

a<br />

b<br />

Culture reverse (PDA) of (a) S. apiospermum and (b) S. aurantiacum showing<br />

production of a light yellow diffusible pigment that is typical of S. aurantiacum.<br />

20 µm<br />

Scedosporium aurantiacum conidiophores (annellides) and conidia.<br />

Antifungal Susceptibility: S. aurantiacum (Australian National data); MIC µg/mL.<br />

No. 64<br />

AmB 11 1 7 3<br />

VORI 11 5 5 1<br />

POSA 11 4 4 2 1<br />

ITRA 11 4 4 3

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