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DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi 173<br />

Rhodotorula mucilaginosa (Jorgensen) Harrison<br />

Synonymy: Rhodotorula rubra (Demme) Lodder.<br />

RG-1 organism.<br />

Morphological Description: Colonies are coral pink, usually smooth, sometimes<br />

reticulate, rugose or corrugated, moist to mucoid, yeast-like colonies. Spherical to<br />

elongate budding yeast-like cells or blastoconidia, 2.5-6.5 x 6.5-14.0 µm.<br />

India Ink Preparation: Small capsules present.<br />

Molecular Identification: Requires sequencing of the ITS and/or D1/D2 regions.<br />

Key Features: Germ tube negative yeast and sugar assimilation pattern. Common<br />

saprophyte however cases of peritonitis and fungaemia have been reported.<br />

Physiological Tests: + Positive, - Negative, v Variable, w Weak, s Slow, nd No Data<br />

Germ Tube - L-Sorbose v L-Arabinose v D-Glucitol v<br />

Fermentation Sucrose + D-Arabinose v α-M-D-glucoside<br />

Glucose - Maltose v D-Ribose v D-Gluconate +<br />

Galactose - Cellobiose v L-Rhamnose v DL-Lactate v<br />

Sucrose - Trehalose + D-Glucosamine v myo-Inositol -<br />

Maltose - Lactose - N-A-D-glucosamine - 2-K-D-gluconate nd<br />

Lactose - Melibiose - Glycerol v D-Glucuronate nd<br />

Trehalose - Raffinose + Erythritol v Nitrate -<br />

Assimilation Melezitose v Ribitol v Urease +<br />

Glucose + Soluble Starch - Galactitol v 0.1% Cycloheximide -<br />

Galactose v D-Xylose + D-Mannitol v Growth at 40 O C +<br />

Antifungal Susceptibility: R. mucilaginosa (Diekema et al. 2005, Australian<br />

National data); MIC µg/mL. Note: Rhodotorula species are intrinsically resistant to<br />

azoles and echinocandins (Arendrup et al. 2014).<br />

No. 64<br />

AmB 39 4 4 5 25 1<br />

FLU 39 39<br />

VORI 37 2 3 6 11 10 4 1<br />

POSA 37 1 3 8 17 2 2 4<br />

ITRA 39 3 8 15 4 1 2 6<br />

5FC 39 1 14 12 11 1

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