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DESCRIPTIONS OF MEDICAL FUNGI

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172<br />

Descriptions of Medical Fungi<br />

RG-1 organism.<br />

Rhodotorula glutinis (Fresenius) Harrison<br />

Morphological Description: Colonies are coral red to salmon-coloured or slightly<br />

orange, smooth to wrinkled, highly glossy to semi-glossy. Mucoid to pasty to slightly<br />

tough, yeast-like colonies. Ovoidal to globose or more elongate budding yeast-like<br />

cells or blastoconidia, 2.3-5.0 x 4.0-10 µm.<br />

India Ink Preparation: Small capsules present.<br />

Molecular Identification: Requires sequencing of the ITS and/or D1/D2 regions.<br />

Key Features: Germ tube negative yeast and sugar assimilation pattern. Common<br />

saprophyte however cases of fungaemia have been reported.<br />

Physiological Tests: + Positive, - Negative, v Variable, w Weak, s Slow, nd No data<br />

Germ Tube - L-Sorbose v L-Arabinose v D-Glucitol v<br />

Fermentation Sucrose + D-Arabinose v α-M-D-glucoside<br />

Glucose - Maltose + D-Ribose v D-Gluconate +<br />

Galactose - Cellobiose v L-Rhamnose v DL-Lactate v<br />

Sucrose - Trehalose + D-Glucosamine - myo-Inositol -<br />

Maltose - Lactose - N-A-D-glucosamine - 2-K-D-gluconate nd<br />

Lactose - Melibiose - Glycerol v D-Glucuronate nd<br />

Trehalose - Raffinose v Erythritol - Nitrate -<br />

Assimilation Melezitose + Ribitol v Urease +<br />

Glucose + Soluble Starch - Galactitol v 0.1% Cycloheximide v<br />

Galactose v D-Xylose v D-Mannitol v Growth at 37 O C v<br />

Antifungal Susceptibility: R. glutinis (Diekema et al. 2005, Australian National<br />

data); MIC µg/mL. Note: Rhodotorula species are intrinsically resistant to azoles<br />

and echinocandins (Arendrup et al. 2014).<br />

No. 64<br />

AmB 38 1 2 4 3 28<br />

FLU 38 38<br />

VORI 36 1 1 12 12 9 1<br />

POSA 34 2 9 18 4 1<br />

ITRA 38 1 1 3 9 11 2 3 8<br />

5FC 38 17 12 8 1

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