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DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi 147<br />

Paecilomyces variotii is a common environmental mould that is widespread in composts,<br />

soils and food products. It is known from substrates including food, indoor air, wood,<br />

soil and carpet dust.<br />

RG-2 organism.<br />

Paecilomyces variotii Bain<br />

Morphological Description: Colonies are fast growing, powdery to suede-like,<br />

funiculose or tufted, and yellow-brown or sand-coloured. Conidiophores bearing<br />

dense, verticillately arranged branches bearing phialides. Phialides are cylindrical or<br />

ellipsoidal, tapering abruptly into a long and cylindrical neck. Conidia are subspherical,<br />

ellipsoidal to fusiform, hyaline to yellow, smooth-walled, 3-5 x 2-4 µm and are produced<br />

in long divergent chains. Chlamydospores are usually present, singly or in short chains,<br />

brown, subspherical to pyriform, 4-8 µm in diameter, thick-walled to slightly verrucose.<br />

Key Features: Yellow-brown colony pigmentation, cylindrical phialides, and presence<br />

of chlamydospores.<br />

a<br />

10 µm b 5 µm c 10 µm<br />

Paecilomyces variotii (a) conidiophores, phialides, (b) conidia<br />

and (c) terminal chlamydospores.<br />

Antifungal Susceptibility: P. variotii (Australian National data); MIC µg/mL.<br />

No. 64<br />

AmB 17 7 3 4 2 1<br />

VORI 17 1 2 1 12 1<br />

POSA 17 5 3 2 5 2<br />

ITRA 17 4 5 5 3

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