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DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi 105<br />

The genus Graphium is characterised by the formation of synnemata which consist<br />

of a more or less compact group of erect conidiophores that are cemented together,<br />

usually splaying out and bearing conidia at the apex. Graphium species are commonly<br />

found on woody plant material. Graphium basitruncatum has been reported as causing<br />

fungaemia in an immunosuppressed child post stem-cell transplantation (El Feghaly<br />

et al. 2012).<br />

Note: Many other fungi such as Scedosporium species may also produce synnemata.<br />

RG-1 organism.<br />

Graphium Corda<br />

Morphological Description: Synnemata are darkly pigmented, erect and occur<br />

solitarily or in clusters. Conidia are hyaline, one-celled, smooth, subglobose to ovoid<br />

and are usually aggregated in slimy heads at the apex of the synnemata. Colonies are<br />

effuse, grey, olivaceous brown or black.<br />

Molecular diagnostics: The genus is phylogenetically close to Scedosporium but ITS<br />

sequencing can be used to resolve all species (Okada et al. 2000, Lackner and de<br />

Hoog 2011).<br />

Key Features: Dematiaceous hyphomycete producing erect synnemata with apical<br />

aggregates of single-celled conidia in slimy heads.<br />

References: Barron (1968), Ellis (1971), McGinnis (1980), de Hoog et al. (2000, 2015).<br />

20 µm<br />

Graphium spp. synnemata and conidia.

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