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DESCRIPTIONS OF MEDICAL FUNGI

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Descriptions of Medical Fungi 97<br />

Fusarium dimerum complex<br />

The Fusarium dimerum complex contains 12 phylogenetically distinct species including<br />

F. delphinoides, F. penzigii and F. dimerum. These are regarded as cosmopolitan<br />

saprotrophs in soil and on plant materials (Domsch et al. 2007). They have also been<br />

isolated from human corneal ulcers after trauma and from disseminated or localised<br />

infections in immunocompromised patients (Schroers et al. 2009, Guarro 2013).<br />

RG-1 organisms.<br />

Morphological Description: Colonies growing slowly; surface usually orange to<br />

deep apricot due to confluent conidial slime; aerial mycelium sometimes floccose and<br />

whitish. Conidiophores loosely branched, with short, often swollen phialides, 10-18 x<br />

4-5 μm. Macroconidia strongly curved and pointed at the apex, mostly one-(some up to<br />

three)-septate, 5-25 (-32) x 1.5-4.2 μm. Microconidia absent. Chlamydospores mostly<br />

intercalary, exceptionally terminal, spherical to ovoidal, 6-12 μm diam, smooth-walled,<br />

single or in chains.<br />

a<br />

b<br />

20 μm<br />

Fusarium dimerum complex (a) culture showing orange to deep apricot<br />

colour due to confluent conidial slime, and (b) macroconidia.<br />

Antifungal Susceptibility: F. dimerum complex (Australian National data); MIC<br />

µg/mL.<br />

No. 64<br />

AmB 21 1 6 6 5 6 2 1<br />

VORI 20 5 8 6 3 3 1<br />

POSA 18 1 4 2 11<br />

ITRA 21 3 24

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