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Dengue Vaccines Market Value Share, Supply Demand, share and Value Chain 2016-2026

Future Market Insights has announced the addition of the “Dengue Vaccines Market: Global Industry Analysis and Opportunity Assessment 2016-2026” report to their offering.

Future Market Insights has announced the addition of the “Dengue Vaccines Market: Global Industry Analysis and Opportunity Assessment 2016-2026” report to their offering.

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Global <strong>Dengue</strong><br />

<strong>Vaccines</strong> <strong>Market</strong><br />

<strong>Share</strong>, Global Trends,<br />

Analysis, Research, Report,<br />

Opportunities,<br />

Segmentation <strong>and</strong> Forecast,<br />

<strong>2016</strong>-<strong>2026</strong><br />

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Report Description<br />

<strong>Dengue</strong> is a mosquito-born flavivirus disease <strong>and</strong> causes dengue fever characterized by<br />

severe headache, skin rash, debilitating muscle, joint pain leaving a feverish feeling. The<br />

dengue virus is also called as ‘breakbone fever’ due to the symptoms it causes. The<br />

symptoms for dengue start appearing in the span of 3-14 days <strong>and</strong> can infect infants,<br />

young children <strong>and</strong> adults. <strong>Dengue</strong> has emerged as one of the critical vector-borne<br />

diseases especially in tropical <strong>and</strong> subtropical regions of the world. The first dengue<br />

vaccine, Dengvaxia (CYD-TDV) developed by Sanofi Pasteur registered in Mexico in<br />

December, 2015. CYD-TDV vaccine is a live recombinant tetravalent dengue vaccine<br />

which was evaluated as a 3 dose series 0/6/12 month schedule in Phase III clinical<br />

studies. There are around five other vaccine c<strong>and</strong>idates under evaluation in clinical trials,<br />

comprising other live-attenuated vaccines, as well as subunit, DNA <strong>and</strong> purified<br />

inactivated vaccine c<strong>and</strong>idates. Along with the developments in dengue vaccines<br />

additional technological approaches, such as virus-vectored <strong>and</strong> VLP-based vaccines, are<br />

held under evaluation in preclinical studies for further advancements.<br />

The development for dengue vaccine had begun by 1929 but was delayed due to the<br />

incomplete knowledge of the diseases. Sanofi Pasture first approved the vaccine for<br />

dengue in 2015 <strong>and</strong> integrated dengue prevention reducing the mortality rate by almost<br />

50%. WHO Strategic Advisory Group of Experts (SAGE) on Immunization reviewed CYD-<br />

TDV in April <strong>2016</strong> <strong>and</strong> recommended countries to introduce the vaccine through its<br />

Global dengue prevention <strong>and</strong> Control Strategy (2012-2020).


Report Description<br />

Request for sample report: http://www.futuremarketinsights.com/reports/sample/repgb-1763<br />

The drivers for dengue vaccine market include growing healthcare concerns, increase in<br />

mortality rate because of dengue fever. And the challenges faced by the scientist in<br />

developing this vaccines were majorly due to the complexity of the dengue virus,<br />

expensive trials <strong>and</strong> time to develop them. After the introduction of Dengvaxia (CYD-<br />

TDV), five additional c<strong>and</strong>idates are I clinical trials. The prices for dengue vaccines are<br />

much higher but due to government intervention the vaccine are sold on discounted<br />

prices in most countries. In March <strong>2016</strong>, Dengvaxia was licensed in Mexico, the<br />

Philippines, Brazil <strong>and</strong> El Salvador for effective prevention against dengue from all four<br />

serotypes which are mostly found in individuals of age 9-45 years living in endemic areas.<br />

According to WHO (World Health Organization) dengue epidemics are being reported<br />

every year from more than 100 endemic countries causing 50-100 million dengue<br />

infections worldwide annually. In the years 2010, 2013 <strong>and</strong> 2015, nearly 2.4 million cases<br />

of dengue had been reported indicating the sharp increase in the number. It was<br />

estimated 500 000 people with severe dengue require hospitalization each year <strong>and</strong> from<br />

them 2.5% of those affected die each year. The dengue vaccine is being produced in in<br />

France in dedicated manufacturing site including a full-scale production capacity of 100<br />

million of vaccine doses annually.


Report Description<br />

In <strong>2016</strong>, Philippines had registered to have the highest incidence of confirmed dengue<br />

among the 10 endemic countries which had participated in clinical efficacy studies for the<br />

vaccine. In April <strong>2016</strong>, the first public dengue immunization program was started in the<br />

Philippines. The major launch event which was hosted by the Department of Health<br />

(DoH) of the Philippines, which lists the details about the country’s plan of vaccinating<br />

about 1 million public school children <strong>and</strong> was <strong>share</strong>d with the international <strong>and</strong> national<br />

press during the event. Where in February, Sanofi Pasteur’s dengue vaccine was firstly<br />

made available for the private sector vaccination in the Philippines<br />

Request for TOC: http://www.futuremarketinsights.com/toc/rep-gb-1763<br />

In the history of global burden of diseases, dengue which bears about 70% of it had an<br />

optimism after the first approval of the vaccine. Due to the developments in the recent<br />

years, pharmaceutical companies have started making effort in developing dengue<br />

vaccine <strong>and</strong> have registered their products for clinical trials. Companies such as<br />

GlaxoSmithKline plc, Merck & Co., Inc. <strong>and</strong> Takeda Pharmaceutical Company Ltd. are each<br />

at different stages in developing the vaccines for dengue.


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