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Blood

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B-<br />

lymphocytes<br />

• :Development<br />

• U.M.C in the bone marrow colony forming cells … lymphoblast . B… .lymphocyte . B<br />

• Percentage: 30% .lymphcytes<br />

• Types:<br />

• B.lymphocytes of humoral immunity.<br />

• B.memory cells.<br />

• :Life span .3months<br />

• Function<br />

• 1- Humoral immunity:<br />

• When exposed to antigen, they are activated into medium sized lymphocytes.<br />

• Some of the active cells are differentiated into plasma cells which produce<br />

antibodies.<br />

• This is called primary immune response.<br />

2- Secondary response (B memory cells):<br />

• Some of the active cells are not changed into plasma cells but remain as memory<br />

cells.<br />

• When exposed to the same antigen again, they produce more rapid and more<br />

extensive humoral immune response.<br />

Dr. Amal M. Moustafa, , Department of Histology & Cytology

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