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UCSF HELEN DILLER FAMILY COMPREHENSIVE CANCER CENTER

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Presentations<br />

Persistence of AR signaling in small cell neuroendocrine prostate<br />

cancer (SCNC) and intermediate atypical carcinoma (IAC): Results from<br />

the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT).<br />

Authors*: Rahul Raj Aggarwal, Jack Youngren, Artem Sokolov, Jiaoti Huang, George V. Thomas,<br />

Lawrence D. True, Adam Foye, Joshi J. Alumkal, Charles J. Ryan, Tomasz M. Beer, Christopher P. Evans,<br />

Martin Gleave, Matthew Rettig, Joshua M. Stuart, Primo Lara, Theodore C. Goldstein, Li Zhang,<br />

Robert Evan Reiter, Kim N. Chi, Eric Jay Small<br />

Abstract #: 5045<br />

Presentation Date/Time: Saturday, June 4: 1:00 - 4:30 PM<br />

Location: Hall A, Poster Board #302<br />

Poster Session: Genitourinary (Prostate) Cancer<br />

Citation: J Clin Oncol 34, 2016 (suppl; abstr 5045)<br />

Small Research Interests: The Stand Up To Cancer Dream Team led by Dr. Eric Small is exploring the<br />

idea that resistance to hormonal therapy occurs as a result of the prostate cancer cells using common<br />

cellular responses - what the Dream Team calls “adaptive pathways” - to escape the current prostate<br />

cancer therapies. They believe that, by identifying these pathways and inhibiting them, they will be able to<br />

overcome treatment resistance and profoundly improve the care of men affected by this fatal disease. This<br />

team is a six institution consortium to include UC Los Angeles, UC Davis, UC Santa Cruz, University of<br />

British Columbia, Oregon Health and Sciences University, with <strong>UCSF</strong> as the lead administrative site.<br />

http://cancer.ucsf.edu/people/profiles/small_eric.3671<br />

*<strong>UCSF</strong> authors in bold<br />

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