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Watch RGCB-the slide show - Rajiv Gandhi Centre for Biotechnology

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M i c r % Reuction o b i of a resazurin l G Dye r o w t h<br />

140<br />

120<br />

100<br />

80<br />

60<br />

40<br />

20<br />

0<br />

Ethyl p-methoxycinnamate: an Anti-TB lead compound.<br />

Source: Kaempferia galanga – a herb used in traditional<br />

medicine <strong>for</strong> TB<br />

Specifically inhibits M. tuberculosis<br />

C Ec Ll Ca Ms Mt<br />

control E. coli L. leischmannii C. albicans M. smegmatis M.tb Rv<br />

H 3 CO<br />

MIC 90 = 250μg/ml<br />

Chemical Modifications<br />

in progress.<br />

C- Control, Ec- Escherichia coli, Ll- Lactobacillus leichmannii, Ca- Candida albicans,<br />

Ms- Mycobacterium smegmatis, Mt- Mycobacterium tuberculosis.

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