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MALARIA ELIMINATION IN ZANZIBAR - Soper Strategies

MALARIA ELIMINATION IN ZANZIBAR - Soper Strategies

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DATA COLLECTION METHODS<br />

A robust surveillance system on Zanzibar will need to incorporate<br />

both passive and active approaches to detecting and reporting<br />

malaria cases. Passive and active case detection have been defined<br />

as follows (Teutsch and Churchill, 2000):<br />

�� Passive case detection–system where data are routinely<br />

received by a central health authority based on a set of rules/<br />

laws that require a healthcare provider or health facility to<br />

report certain diseases or conditions on an ongoing basis and<br />

at specific intervals (weekly, monthly, annually).<br />

�� Active case detection–system where data are regularly pursued<br />

by a central health authority at periodic intervals, often with the<br />

intent to validate the representativeness of a passive surveillance<br />

system. An active surveillance system will likely provide more<br />

complete reporting, and can identify asymptomatic individuals,<br />

but it is more labor intensive and thus more costly to operate as<br />

compared to passive case detection.<br />

There is relatively little central guidance on both of these<br />

approaches for malaria elimination. This lack exists because<br />

they are highly context dependent and must be adapted to each<br />

country and area.<br />

Passive Case Detection (PCD)<br />

A strong passive case detection system is the cornerstone of<br />

any approach to surveillance–if new malaria cases identified at<br />

health facilities are not being adequately reported and followed<br />

up, elimination will not be achieved. In Zanzibar, the passive<br />

case detection system will have to be substantially improved to<br />

ensure that a high proportion of infections are detected (both<br />

symptomatic and asymptomatic) and reported to the central level<br />

with the required speed (e.g., initially within 24 hours but once<br />

at or near zero local transmission as soon as possible). From the<br />

results of the simulations described in the Technical Feasibility<br />

Chapter we know that as long as preventive measures have an<br />

effective coverage of 75%:<br />

�� Between 70-80% of infections have to be promptly identified<br />

and treated for passive case detection alone to be sufficient to<br />

avoid second-generation infections.<br />

�� Passive case detection that identifies around 50% of all<br />

infections–a detection rate only slightly higher than the<br />

present day–will need to be complemented with active case<br />

detection that screens about 100 households neighboring<br />

each newly identified case.<br />

Achieving the required detection levels is influenced by a range of<br />

factors: the fraction of infections that will become symptomatic,<br />

the people’s health seeking behavior for fever, testing rates at<br />

the facility, and the sensitivity of the test used. The operational<br />

requirements for the surveillance system to achieve the above<br />

mentioned detection levels are described below.<br />

In addition, the Zanzibar MOHSW will need to strengthen the<br />

central units that record and analyze cases that are reported by<br />

increasing human resources, improving skills, and obtaining<br />

appropriate technology.<br />

2 | Operational Feasibility<br />

Current System<br />

There are currently two systems for passive detection of malaria<br />

cases on Zanzibar: the Health Management Information System<br />

(HMIS) and a vertical Malaria Early Epidemic Detection System<br />

(MEEDS) through sentinel sites (52 sites operational in 2009).<br />

The HMIS is managed by a specific unit in the MOHSW that<br />

was established in 2001 and strengthened through funding from<br />

DANIDA. The HMIS serves as the primary clinical services<br />

monitoring system for the MOHSW and fits within the larger<br />

context of health sector M&E efforts in Zanzibar. Data from<br />

peripheral facilities are collected by the HMIS focal point at the<br />

district level. Aggregated data are compiled at the district level<br />

and sent to the HMIS unit in the MOHSW.<br />

Malaria information collected as part of the HMIS is supposed<br />

to be reported quarterly through District Health Management<br />

Teams (DHMT) and provincial offices. The cases reported are<br />

both (parasitological) confirmed and non-confirmed based on<br />

clinical diagnosis and therefore include non-malarious fever<br />

cases. Although most facilities have diagnostic capacity (RDT<br />

and/or microscopy) and the results are supposed to be captured<br />

in the laboratory reports, the HMIS is currently not providing<br />

this information to the ZMCP. The following indicators are<br />

theoretically available through routine HMIS:<br />

�� Out Patient Department monthly malaria cases (both<br />

confirmed and non-confirmed)<br />

�� Laboratory data (total slides, positive films for malaria<br />

parasites, hemoglobin tests)<br />

�� Malaria and severe anemia admissions and deaths<br />

Unfortunately, the information collected through the HMIS<br />

system is not routinely passed on to the different control programs<br />

within the MOHSW. The ZMCP therefore decided to collect<br />

malaria data for their strategic planning using 6 health facilitybased<br />

sentinel surveillance sites (HFBSS). These sites are part of<br />

the normal HMIS and do not report different information as such.<br />

The main difference is that the HFBSS provide regular, timely,<br />

high-quality malaria-related laboratory, morbidity, and mortality<br />

data, an important pillar for the ZMCP strategic decision. The<br />

MEEDS (see below) now provides these data regularly, and the<br />

HFBSS will most probably be scaled down and even stopped in<br />

the near future.<br />

The second existing malaria surveillance system, malaria<br />

early epidemic detection system (MEEDS), is connected to<br />

a broader effort by the MOHSW to strengthen infectious<br />

disease surveillance. It is funded by PMI and uses mobile phone<br />

technology to provide weekly malaria data to a central server<br />

where they are automatically analyzed. It provides aggregate<br />

data (for under fives and over fives) on total number of patients<br />

seen at the facility, total numbers tested and numbers testing<br />

positive. The MEEDS is so far the only operational component<br />

of the planned Integrated Diseases Surveillance and Response<br />

(IDSR) that aims at providing health workers with additional<br />

epidemiological information on key diseases to assist in decisionmaking<br />

on and implementation of interventions As the MEEDS<br />

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