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UCSF HELEN DILLER FAMILY COMPREHENSIVE CANCER CENTER

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Presentations<br />

Off-target resistance to inhibitors of BCR-ABL and FLT3 in<br />

myeloid malignancies<br />

Authors*: Neil P. Shah<br />

Pres #: Section: Presentation Date/Time: Monday, April 18: 2:00-2:25PM<br />

Location: Room 265<br />

Presentation Type: Recent Advances in Organ Site Research<br />

Shah Lab Expertise : The Shah lab is interested in advancing targeted therapeutics for hematologic<br />

malignancies through basic studies of in vitro and in vivo model systems to gain a better understanding<br />

critical vulnerabilities of malignant cells, and through translational/clinical studies of samples obtained<br />

from patients participating in early phase monotherapy clinical studies to identify, validate and override<br />

mechanisms of resistance to these agents.<br />

https://shah.ucsf.edu/<br />

__________________________________________________________________________<br />

Translation of hyperpolarized 13 C imaging to the clinic<br />

Authors*: John Kurhanewicz<br />

Pres #: Section: Presentation Date/Time: Monday, April 18: 2:10-2:35PM<br />

Location: Room 260 Presentation Type: Major Symposium<br />

Kurhanewicz Lab Expertise<br />

__________________________________________________________________________<br />

Targeting adaptive pathways in metastatic treatment resistant<br />

prostate cancer<br />

Authors*: Eric Small<br />

Pres #: Section: Presentation Date/Time: Monday, April 18: 3:28-3:51PM<br />

Location: Room 243<br />

Presentation Type: Special Session<br />

Small Lab Expertise: The Stand Up To Cancer Dream Team led by Dr. Eric Small is exploring the idea<br />

that resistance to hormonal therapy occurs as a result of the prostate cancer cells using common cellular<br />

responses — what the Dream Team calls “adaptive pathways” — to escape the current prostate cancer<br />

therapies. They believe that, by identifying these pathways and inhibiting them, they will be able to overcome<br />

treatment resistance and profoundly improve the care of men affected by this fatal disease. This team is a six<br />

institution consortium to include UC Los Angeles, UC Davis, UC Santa Cruz, University of British Columbia,<br />

Oregon Health and Science University, with <strong>UCSF</strong> as the lead administrative site.<br />

http://cancer.ucsf.edu/people/profiles/small_eric.3671<br />

*<strong>UCSF</strong> authors in bold<br />

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