UCSF HELEN DILLER FAMILY COMPREHENSIVE CANCER CENTER
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Presentations<br />
Primary analysis of the EORTC 10041/ BIG 3-04 MINDACT study:<br />
A prospective, randomized study evaluating the clinical utility<br />
of the 70-gene signature (MammaPrint) combined with common<br />
clinical pathological criteria for selection of patients for adjuvant<br />
chemotherapy in breast cancer with 0 to 3 positive nodes<br />
Authors*: Martine Piccart, Emiel Rutgers, Laura van’ t Veer, Leen Slaets, Suzette Delaloge, Giuseppe Viale,<br />
Jean Yves Pierga, Peter Vuylsteke, Etienne Brain, Suzan Vrijaldenhoven, P. Neijenhuis, Bruno Coudert,<br />
Tineke Smilde, Miguel Gil, Alastair Thompson, Isabel Rubio, Rodolfo Passalaqua, Erika Matos, Urlike Nitz,<br />
Mauro Delorenzi, Geraldine Thomas, Theodora Goulioti, Carolyn Straehle, Konstantinos Tryfonidis,<br />
Jan Bogaerts, Fatima Cardoso<br />
Pres #: CT039 Section: Presentation Date/Time: Monday, April 18: 10:30-10:50AM<br />
Location: La Nouvelle Orleans Ballroom<br />
Presentation Type: Clinical Trials Plenary Session<br />
van ‘t Veer Lab Expertise: Dr. van ’t Veer’s research focuses on personalized medicine & advancing patient<br />
management based on knowledge of the genetic makeup of the tumor as well as the genetic makeup of the<br />
patient. Her laboratory investigates human kinases & how kinase inhibitors elicit response & resistance, which<br />
is also utilized to understand agent efficacy in the I-SPY 2 TRIAL. She is the PI of the Athena Breast Health<br />
Network, a 150,000 women cohort study evaluating new paradigms to enhance breast health. She leads the<br />
targeted genome testing of 100,000 women for 9 breast cancer susceptibility genes and a selection of ~100<br />
known susceptibility SNPs. She is one of the PIs for the NIH Big Data to Knowledge Center Translational<br />
Genomics, facilitating worldwide standardization of sharing annotated genomics data.<br />
http://cancer.ucsf.edu/people/profiles/vantveer_<br />
__________________________________________________________________________<br />
Targeting KRAS stemness<br />
Authors*: Frank McCormick<br />
Pres #: Section: Presentation Date/Time: Monday, April 18: 10:40-11:05AM<br />
Location: New Orleans Theater A<br />
Presentation Type: Major Symposium<br />
__________________________________________________________________________<br />
Translating genomic discoveries into therapy for<br />
acute lymphoblastic leukemia<br />
Authors*: Mignon L. Loh<br />
Pres #: Section: Presentation Date/Time: Monday, April 18: 11:30-11:55AM<br />
Location: Room 260<br />
Presentation Type: Recent Advances in Diagnostics and Therapeutics Research<br />
*<strong>UCSF</strong> authors in bold<br />
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