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UCSF HELEN DILLER FAMILY COMPREHENSIVE CANCER CENTER

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Presentations<br />

Interaction between meat and fish intake and genes involved<br />

in hormones, inflammation and energetic factors, and risk of<br />

breast cancer among Hispanic and Non-Hispanic White women:<br />

The Breast Cancer Health Disparities Study<br />

Authors*: Andre E. Kim, Juan Pablo Lewinger, Shirong Zhang, Roger K. Wolff, Laura Fejerman, Esther M. John,<br />

Gabriela Torres-Mejia, Jennifer S. Herrick, Stephanie D. Boone, Avonne E. Connor, Lisa M. Hines,<br />

Kathy B. Baumgartner, Anna Giuliano, Martha L. Slaeery, Mariana C. Stern<br />

Pres #: 799 Section: 36 Presentation Date/Time: Sunday, April 17: 1:00-5:00PM<br />

Location:<br />

Presentation Type: Poster Session<br />

Fejerman Lab Expertise: Dr. Fejerman focuses on the discovery of genetic and non-genetic factors that<br />

contribute to breast cancer risk and prognosis in Latinas. Her past work established a relationship between<br />

genetic ancestry and breast cancer risk, where higher European ancestry in U.S. and Mexican Latinas was<br />

associated with an increased risk. Her subsequent research has built upon this observation, exploring genetic<br />

variants, through admixture mapping and genome-wide association approaches, as well as the possible<br />

environmental and lifestyle related factors, and ancestry-gene interactions. Recent work explores disparities in<br />

breast cancer prognosis by genetic ancestry in Latinas and its potential causes.<br />

http://fejerman.ucsf.edu<br />

__________________________________________________________________________<br />

Combining sensitivity markers to identify triple-negative<br />

breast cancer patients most responsive to veliparib/carboplatin:<br />

results from the I-SPY 2 TRIAL<br />

Authors*: Denise M. Wolf, Christina Yau, Ashish Sanil, Larmorna Brown-Swigart, Gillian<br />

Hirst, Meredith Buxton, Melissa Paolini, Olufunmilayo Olopade, Hope Rugo, Angela De Michele,<br />

Fraser Symmans, Don Berry, Laura Esserman, Laura van ‘t Veer<br />

Pres #: 858 Section: Presentation Date/Time: Sunday, April 17: 5:35-5:50PM<br />

Location: Room 391<br />

Presentation Type: Minisymposium<br />

van ‘t Veer Lab Expertise: Dr. van ’t Veer’s research focuses on personalized medicine & advancing patient<br />

management based on knowledge of the genetic makeup of the tumor as well as the genetic makeup of the<br />

patient. Her laboratory investigates human kinases & how kinase inhibitors elicit response & resistance, which<br />

is also utilized to understand agent efficacy in the I-SPY 2 TRIAL. She is the PI of the Athena Breast Health<br />

Network, a 150,000 women cohort study evaluating new paradigms to enhance breast health. She leads the<br />

targeted genome testing of 100,000 women for 9 breast cancer susceptibility genes and a selection of ~100<br />

known susceptibility SNPs. She is one of the PIs for the NIH Big Data to Knowledge Center Translational<br />

Genomics, facilitating worldwide standardization of sharing annotated genomics data.<br />

http://cancer.ucsf.edu/people/profiles/vantveer_laura.3358<br />

*<strong>UCSF</strong> authors in bold<br />

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